Active Studies

  • Study TitleAge-Adjusted D-dimer cut-off levels to rule out deep vein thrombosis: A prospective outcome study (Adjust-DVT)

Study Site: FMC

Start Date: July 2017

 Objective: Evaluate whether an age-adjusted d-dimer cutoff can be safely used to rule out DVT.

Study Population: Patients aged 18 and older with a clinically suspected DVT of the leg. Patients aged 18-49 will receive standard of care. Patients 50 and older will receive intervention.

Study Intervention: Utilization of age-adjusted d-dimer (10 ug/L x age in years) to guide DVT care pathway. Patients with a Wells <2 will only have an ultrasound if d-dimer exceeds age-adjusted cutoff. Patients 50 and over with Wells ?2 will receive an initial ultrasound at ED visit. If initial ultrasound is negative, patients will only receive a serial ultrasound if d-dimer exceeds age-adjusted cutoff.

 

What is being asked of physicians?

-          Confirm inclusion/exclusion criteria with RAs

-          Manage patients with suspected DVT according to age-adjusted d-dimer results and Wells score

 

  • Study Title: Demographic and Regional Variation of Drug-Impaired Driving in Canada [DID]

    Study Site: FMC

    Start Date: May 2018

    Objective:

    Overarching goal: To provide relevant data that will be used by policy makers to inform and evaluate policy and programs designed to prevent drug-impaired driving in Canada.

    Objective 1: To describe the prevalence and pattern of drug-impaired driving in Canada.

    1.1 What proportion of injured drivers test positive for alcohol, COOH-THC, THC, cocaine, amphetamines, opiates, benzodiazepines, antihistamines, antidepressants, or antipsychotics? 

    1.2 What are the common drug combinations?

    1.3 Which driver and crash characteristics (age, sex, socio-economic status (SES), rural versus urban, single versus multi-vehicle, time of day) are most closely associated with the use of different drugs?

    1.4 Is there regional variation in the prevalence and pattern of drug-impaired driving in Canada?

    Objective 2: Estimate the percentage and population attributable fraction of crashes associated with drug-impaired driving in Canada.

    Study Population: Confirmed drivers involved in a MVC or MBC greater than the age of 16 and have a clinical CBC drawn within 6 hours of the documented crash time.

    Study Intervention: No direct intervention to patients – this study is waiver of consent. Patients are only enrolled if they meet the study population criteria, and the RA on shift will collect demographic information using the patients chart/SCM, and coordinate with the hematology lab to hold the blood sample which will be sent to UBC for a toxicology analysis.

    What is being asked of physicians?

    Nothing! As this study is waiver of consent, the RA team will be collecting the information without needing any additional information from you.