Calgary Normative Study


Calgary Normative Study

The Calgary Normative Study (CNS) is an ongoing, longitudinal study of normal human brain aging whihc focuses on acquiring quantitative MR imaging structural and functional data. The CNS began in 2014 and to date over 450 subjects have been enrolled (18-90+ years) with over 200 subjects having had follow-up imaging after a period of approximately 3.5 years. We anticipate enrolling additional subjects and acquiring follow up data at 7 years and later.

Each subject receives an imaging battery (including T1 morphology, perfusion and diffusion imaging, resting state fMRI, quantitative susceptibility mapping), resting-state fMRI and T1 and T2 relaxometry, plus a simple cognitive test and acquisition of a medical history. See our "protocol" paper:

Representative Publications

Prospective Trainee Requirements

Interest in aging, disease of aging, and imaging with a degree (MSc preferred) in Biomedical, Computer, or Electrical Engineering. Suitable candidates with degrees in Health Sciences, Medical Sciences or Neurosciences may also be appropriate for this project. A good grasp of MR imaging, image processing techniques, and statistics would be highly beneficial. Must have good oral and written English communication skills.