Publication Highlights

Our team has contributed to the following publications

The CanCOLD Study

2023

Factors associated with attrition in a longitudinal cohort of older adults in the community 

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Physical activity and symptom burden in COPD: the Canadian Obstructive Lung Disease study

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Impaired spirometry and chronic obstructive pulmonary disease increase the risk of cardiovascular disease: a Canadian cohort study 

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2022

Ambient air pollution and dysanapsis: associations with lung function and chronic obstructive pulmonary disease in the Canadian Cohort Obstructive Lung Disease Study

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Impaired ventilatory efficiency, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease: results from the CanCOLD study

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2021

Dyspnoea and symptom burden in mild-moderate COPD: the Canadian Cohort Obstructive Lung Disease study

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The prevalence of chronic obstructive pulmonary disease (COPD) and the heterogeneity of risk factors in the Canadian population: results from the Canadian Obstructive Lung Disease (COLD) study

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High eosinophil counts predict decline in FEV1: results from the CanCOLD study

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2020

Identification and definition of asthma-COPD overlap: the CanCOLD study

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2019

The effects of marijuana smoking on lung function in older people

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Impaired sleep quality in COPD is associated with exacerbations: the CanCOLD cohort study

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Physiological distress is related to poor health behaviours in COPD and non-COPD patients: evidence from the CanCOLD study

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2018

Global initiative for chronic obstructive lung disease 2017 classification and lung function decline in chronic obstructive pulmonary disease

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Total airway count on computed tomography and the risk of chronic obstructive pulmonary disease progression. Findings from a population-based study

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2017

Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study

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2016

The COPD assessment test: can it discriminate across COPD subpopulations?

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Findings on thoracic computed tomography scans and respiratory outcomes in persons with and without chronic obstructive pulmonary disease: a population-based cohort study

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Undiagnosed chronic obstructive pulmonary disease contributes to the burden of health care use. Data from the CanCOLD study

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Undiagnosed COPD and Asthma Population (UCAP) Study

2023

Assessment of Preserved Ratio Impaired Spirometry Using Pre- and Post-Bronchodilator Spirometry in a Randomly Sampled Symptomatic Cohort

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Patient and physician factors associated with symptomatic undiagnosed asthma or COPD

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Impact of Undiagnosed Chronic Obstructive Pulmonary Disease and Asthma on Symptoms, Quality of Life, Healthcare Use, and Work Productivity

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2022

Disease burden in individuals with symptomatic undiagnosed asthma or COPD

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Derivation and validation of the UCAP-Q case-finding questionnaire to detect undiagnosed asthma and COPD

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2020

Population-based case-finding to identify subjects with undiagnosed asthma or COPD

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DESTINATION

2023

Long-term safety and efficacy of Tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study

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NAVIGATOR

2021

Tezepelumab in adults and adolescents with severe, uncontrolled asthma

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2020

NAVIGATOR: a phase 3 multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of Tezepelumab in adults and adolescents with severe, uncontrolled asthma

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CASCADE

2020

CASCADE: a phase 2, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of tezepelumab on airway inflammation in patients with uncontrolled asthma

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SABA use IN Asthma (SABINA) Study

2023

Beware SABA Overuse: a Message from the Global SABINA Program

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2022

Short-acting beta-2-agonist exposure and severe asthma exacerbations: SABINA findings from Europe and North America

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SABA use as an indicator for asthma exacerbation risk: an observational cohort study (SABINA Canada)

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ANDHI

2021

Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patient with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial

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The Asthma Diagnosis Study

2020

Performance characteristics of spirometry with negative bronchodilator response and methacholine challenge testing and implications for asthma diagnosis

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2017

Reevaluation of diagnosis in adults with physician-diagnosed asthma

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2016

Establishing a correct diagnosis in adults who have been mis-diagnosed with asthma

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COPD Transition Bundle Intervention

2023

Cost analysis of a transition care bundle compared with usual care for COPD patients being discharged from hospital: evaluation of a randomized control trial 

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2022

Optimizing COPD acute care patient outcomes using a standardized transition bundle and care coordinator: a randomized clinical trial

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2020

Factors influencing the implementation and uptake of a discharge care bundle for patients with acute exacerbation of chronic obstructive pulmonary disease: a qualitative focus group study

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Other

2023

Canadian multidisciplinary expert consensus on the use of biologics in upper airways: a Delphi study

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Medication use of Canadians with chronic obstructive pulmonary disease: a cohort study

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Effectiveness of Benralizumab after 12 months of treatment in Canadians with Severe Asthma

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A population-based study of the burden of severe asthma in Alberta, Canada

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The risk of exacerbation with elevated biomarkers, and real-world biomarker variability, in patients with severe asthma: a retrospective, population-based study

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2023 Canadian Thoracic Society guideline on pharmacotherapy in patients with stable COPD

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Canadian health care professionals' familiarity with chronic cough guidelines and experiences with diagnosis and management: a cross-sectional survey

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Inhaled anti-TSLP antibody fragment, ecleralimab, blocks responses to allergen in mild asthma

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Sounding the alarmins - the role of alarmin cytokines in asthma

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2022

Assessing cough symptom severity in refractory or unexplained chronic cough: findings from patient focus groups and an international expert panel 

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Effects of traffic-related air pollution on exercise endurance, dyspnea, and cardiorespiratory responses in health and COPD: a randomized, placebo-controlled, crossover trial

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Long-term modulation of airway remodeling in severe asthma following bronchial thermoplasty

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2021

Transcriptome-level interactions between budesonide and formoterol provide insight into the mechanism of action of inhaled corticosteroid/long-acting β2-adrenoceptor agonist combination therapy in asthma

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2019

A drug safety review of treating eosinophilic asthma with monoclonal antibodies 

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Omalizumab in patients with severe asthma and persistent sputum eosinophilia

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Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

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Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma

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