Research Studies
We are currently recruiting for the following research studies. Participants must be at least 18 years of age.
Research
Our research aims to better the mechanistic understanding of autonomic disorders and improve therapy options for these conditions.
Find publications by our investigators, current clinical trials, and links to external research efforts.
Dr. Satish R Raj, MD MSCI
Research interests: postural tachycardia syndrome; vasovagal syncope; autonomic nervous system failure
Dr. Jacquie Baker, PhD
Research interests: autonomic failure, orthostatic intolerance
Dr. Robert Sheldon, MD PhD
Research interests: syncope; atrial fibrillation
Looking for additional peer-reviewed literature? See more.
Body Compression in POTS: Effects on Orthostatic Intolerance
A study investigating the effects of abdominal and leg compression on orthostatic heart rate change and orthostatic symptoms in individuals diagnosed with POTS. A segmented, non-inflatable compression garment (neoprene with velcro straps) will be used to apply compression to all or portions of the lower body.
The Pathophysiological Role of Adrenergic Antibodies in POTS
A pilot study involving autonomic function testing (AIM #1), small doses of short acting medications (AIM #2), and a longer medication trial (AIM #3) to evaluate the role of antibodies in cardiovascular regulation in POTS patients as compared to healthy volunteers. POTS participants are invited back for follow-up examination one year following the study. All participants are required to complete an online questionnaire.
Recently Completed Research Studies
Prevention of Syncope Trial VI (POST 6)
A placebo-controlled proof of principle study in patients with recurrent vasovagal syncope, to examine whether the drug Atomoxetine will better prevent syncope in head up tilt testing than placebo. Atomoxetine is a drug that is currently approved for the treatment of attention-deficit hyperactivity disorder (ADHD).
More Research Information
The following external resources provide additional information on specific assessment methods, previous findings, and future directions within the field of autonomic disorder research.