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Research

Learn about our clinical research and how we use neuroimaging to investigate drug-resistant focal epilepsy

Our lab utilizes cutting edge functional and structural brain imaging techniques to study people with epilepsy whose seizures cannot be adequately controlled with medication. Our research aims to help improve surgical outcome and increase quality of life.

We are currently only one of two centres worldwide to utilize intracranial EEG-fMRI, a technique that combines the temporal accuracy of EEG with the spatial coverage of fMRI. We are also investigating novel interictal (between seizures) markers of seizure-generating tissue as well as exploring the physiological changes in the brain following a seizure.

Find out more about our research areas below.

Sample of EEG-fMRI

Intracranial EEG fMRI

Removal of tissue associated with seizures requires accurate neuroimaging techniques to guide surgeries. By leveraging the best of EEG and MRI imaging, we can more accurately identify tissue involved in generating seizures.

Example of an HFO on an IED

High Frequency Oscillations

Seizures often leave clues about their origin on EEG when patients are monitored at the hospital. We are investigating a promising novel EEG marker that reveals pathologic tissue without patients having a seizure.

Example of perfusion changes

Postictal Hypoperfusion

Seizures are not just an electrical phenomena, they also alter how the brain circulates blood and which regions are fed. We are currently exploring long-term changes in brain vascular dynamics following seizures.

We publish frequently in our areas of research. Click to view our publications