Welcome to the Lahl Lab

The core interest of the Lahl lab lies in the recognition of viruses by the mucosal immune system. We focus on dendritic cells subset biology and function with an emphasis on IgA induction at the mucosal surface. Our combined expertise in mucosal immunology, virology, and immune tolerance induction allows us a holistic view of the cellular players within the delicate ecosystem that maintains immune homeostasis at barrier surfaces. We hypothesize that early-life viral infections impact on the healthy establishment of barrier and systemic immunity and use enteric/respiratory infection and immunopathology models to interrogate the cellular basis of neonatal immune imprinting and its consequences for life-long health.

• Our paper on Bcl6 in cDC subsets is finally out in Nature Communications! (https://www.nature.com/articles/s41467-024-46966-6)
• Welcome to PURE summer student Delaney Robinson-Wong!
• Congrats to Signe for receiving a CBW Travel Award to attend the single cell RNA-seq analysis workshop in Toronto in June!
• Congratulations to Simone for receiving an MIID sponsored travel award to attend CSI2024!
• Here is our view on a recent JEM paper clarifying the source of IL-23 in the intestines: (https://doi.org/10.1084/jem.20232144 )