Publications

Identification and characterization of antigen-specific T-cells in viral infections.
Trubach D, Muleta KG, Lahl K, Saini SK. Methods Mol Biol. 2024;2813:295-308. doi: 10.1007/978-1-0716-3890-3_19.
 

Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses.
Xiao H, Ulmert I, Bach L, Huber J, Narasimhan H, Kurochkin I, Chang Y, Holst S, Mörbe U, Zhang L, Schlitzer A, Pereira CF, Schraml BU, Baumjohann D, Lahl K. Nat Commun. 2024 Apr 30;15(1):3554. doi: 10.1038/s41467-024-46966-6.
 

Migratory CD103+CD11b+ cDC2s in Peyer's patches are critical for gut IgA responses following oral immunization.
Gribonika I, Strömberg A, Chandode RK, Schön K, Lahl K, Bemark M, Lycke N. Mucosal Immunol. 2024 Mar 15:S1933-0219(24)00023-0. doi: 10.1016/j.mucimm.2024.03.004.
 

IL-23 to see: Gut DCs shine bright in inductive sites. 
Ulmert I, Lahl K. J Exp Med. 2024 Feb 5;221(2):e20232144. doi: 10.1084/jem.20232144.  
 

Guidelines for DC preparation and flow cytometry analysis of mouse nonlymphoid tissues. 
Probst HC, Stoitzner P, Amon L, Backer RA, Brand A, Chen J, Clausen BE, Dieckmann S, Dudziak D, Heger L, Hodapp K, Hornsteiner F, Hovav AH, Jacobi L, Ji X, Kamenjarin N, Lahl K, Lahmar I, Lakus J, Lehmann CHK, Ortner D, Picard M, Roberti MP, Rossnagel L, Saba Y, Schalla C, Schlitzer A, Schraml BU, Schütze K, Seichter A, Seré K, Seretis A, Sopper S, Strandt H, Sykora MM, Theobald H, Tripp CH, Zitvogel L. Eur J Immunol. 2023 Nov;53(11):e2249819. doi: 10.1002/eji.202249819.
 

A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut. 
Vergani S, Muleta KG, Da Silva C, Doyle A, Kristiansen TA, Sodini S, Krausse N, Montano G, Kotarsky K, Nakawesi J, Åkerstrand H, Vanhee S, Gupta SL, Bryder D, Agace WW, Lahl K, Yuan J. Immunity. 2022 Oct 11;55(10):1829-1842.e6. doi: 10.1016/j.immuni.2022.08.018.
 

Type I interferons promote germinal centers through B cell intrinsic signaling and dendritic cell dependent Th1 and Tfh cell lineages. 
Dahlgren MW, Plumb AW, Niss K, Lahl K, Brunak S, Johansson-Lindbom B. Front Immunol. 2022 Jul 13;13:932388. doi: 10.3389/fimmu.2022.932388.
 

Rotavirus-induced expansion of antigen-specific CD8 T cells does not require signaling via TLR3, MyD88 or the Type I interferon receptor. 
Muleta KG, Ulmert I, Hamza KH, van Dijl S, Nakawesi J, Lahl K. Front Immunol. 2022 Apr 7;13:814491. doi: 10.3389/fimmu.2022.814491.
 

ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection. 
Arabpour M, Lebrero-Fernandez C, Schön K, Strömberg A, Börjesson V, Lahl K, Ballegeer M, Saelens X, Angeletti D, Agace W, Lycke N. Mucosal Immunol. 2022 Apr;15(4):745-761. doi: 10.1038/s41385-022-00510-1.
 

The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus. 
Jørgensen AS, Brandum EP, Mikkelsen JM, Orfin KA, Boilesen DR, Egerod KL, Moussouras NA, Vilhardt F, Kalinski P, Basse P, Chen YH, Yang Z, Dwinell MB, Volkman BF, Veldkamp CT, Holst PJ, Lahl K, Goth CK, Rosenkilde MM, Hjortø GM. Cell Mol Life Sci. 2021 Nov;78(21-22):6963-6978. doi: 10.1007/s00018-021-03930-7.
 

Minor alterations in the intestinal microbiota composition upon Rotavirus infection do not affect susceptibility to DSS colitis. 
Hamza KH, Dunér E, Ulmert I, Arias A, Sorobetea D, Lahl K. Sci Rep. 2021 Jun 29;11(1):13485. doi: 10.1038/s41598-021-92796-7.
 

Rotavirus infection causes mesenteric lymph node hypertrophy independently of type I interferon or TNF-α in mice. 
Nakawesi J, Konjit GM, Dasoveanu DC, Johansson-Lindbom B, Lahl K. Eur J Immunol. 2021 May;51(5):1143-1152. doi: 10.1002/eji.202048990.
 

αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus. 
Nakawesi J, This S, Hütter J, Boucard-Jourdin M, Barateau V, Muleta KG, Gooday LJ, Thomsen KF, López AG, Ulmert I, Poncet D, Malissen B, Greenberg H, Thaunat O, Defrance T, Paidassi H, Lahl K. Mucosal Immunol. 2021 Jan;14(1):53-67. doi: 10.1038/s41385-020-0276-8.
 

Mononuclear phagocyte regulation by the transcription factor Blimp-1 in health and disease. 
Ulmert I, Henriques-Oliveira L, Pereira CF, Lahl K. Immunology. 2020 Dec;161(4):303-313. doi:10.1111/imm.13249.
 

Migration of murine intestinal dendritic cell subsets upon intrinsic and extrinsic TLR3 stimulation. 
Garcias López A, Bekiaris V, Müller Luda K, Hütter J, Ulmert I, Getachew Muleta K, Nakawesi J, Kotarsky K, Malissen B, O'Keeffe M, Holzmann B, Winston Agace W, Lahl K. Eur J Immunol. 2020 Oct;50(10):1525-1536. doi:10.1002/eji.201948497.
 

Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization. 
Zhang B, Liu E, Gertie JA, Joseph J, Xu L, Pinker EY, Waizman DA, Catanzaro J, Hamza KH, Lahl K, Gowthaman U, Eisenbarth SC. Sci Immunol. 2020 May 8;5(47):eaay2754. doi: 10.1126/sciimmunol.aay2754.