Yu Gui

Yu Gui

Education

  • M. D. SUN Yet-Sen Medical University, Guangzhou, P. R. China.
  • Ph.D. Dept. of Pharmacology, University of Calgary, Alberta, Canada.
  • Postdoctoral Fellow Dept. of Biochemistry & Molecular Biology, University of Calgary, Alberta, Canada.

Scholarship awards

2010 – 2012    Grant-in Aid Grant, Heart & Stroke Foundation of Canada (Principal Investigator)

2007 – 2009    Fellowship Award from Alberta Heritage foundation for Medical Research

2004 – 2006    Fellowship Award from the Heart & Stroke Foundation of Canada

 

Publications (Selected from over 35 peer-reviewed publications)

  1. Guo Y, Tang Z, Yan B, Yin H, Tai S, Peng J, Cui Y, Gui Y, Belke D, Zhou S, Zheng XL. PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease. Arterioscler Thromb Vasc Biol. 42(1):67-86, 2022
  2. Gui Y, Shi Z, Wang ZY, Li J.J., Xu C, Tian R.J., Song XX, Walsh MP, Li D, Gao J, Zheng XL. The GPER agonist G-1 induces mitotic arrest and apoptosis in human vascular smooth muscle cells independent of GPER. J Cell Physiol. 230: 885-95, 2015
  3. Gui Y*, Wang Z, Sun X, Walsh MP, Li JJ, Gao J and Zheng XL: Uridine adenosine tetraphosphate induces contraction of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 301(5):L789-94, 2011 (*Senior author)
  4. Gao G, Li JJ, Li Y, Li D, Wang Y, Wang L, Tang XD, Walsh MP, Gui Y* and Zheng XL*: Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility. Am J Physiol Heart Circ Physiol 300: H1583-94, 2011 (*Co-Senior author)
  5. Cui L, Ren Y, Yin H, Wang Y, Li D, Liu M, Zhu Y, Lin W, Tang XD, Gui Y* and Zheng XL*: Increased expression of tuberin in human uterine leiomyoma. Fertil Steril 95: 1805-8, 2011 (*Co-Senior author)
  6. Gui Y, Zheng XL, Zheng J and Walsh MP: Inhibition of rat aortic smooth muscle contraction by 2-methoxyestradiol. Am J Physiol Heart Circ Physiol 295: H1935-42, 2008
  7. Gui Y, Walsh MP, Jankowski V, Jankowski J and Zheng XL: Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery. Am J Physiol Lung Cell Mol Physiol 294: L733-8, 2008
  8. Gui Y, He GH, Walsh MP and Zheng XL: Predisposition to tetraploidy in pulmonary vascular smooth muscle cells derived from the Eker rats. Am J Physiol Lung Cell Mol Physiol 293: L702-11, 2007
  9. Gui Y and Zheng XL: 2-methoxyestradiol induces cell cycle arrest and mitotic cell apoptosis in human vascular smooth muscle cells. Hypertension 47: 271-80, 2006
  10. Gui Y and Zheng XL: Epidermal growth factor induction of phenotype-dependent cell cycle arrest in vascular smooth muscle cells is through the mitogen-activated protein kinase pathway. J Biol Chem 278: 53017-25, 2003

 

Hobbies