Peer Reviewe Journals, Published

  1. M. Kapoor, M.D. O'Brien, D.Quon and B.W. Winston.  Studies on the Structure-function Relationships of Neurospora crassa Pyruvate Kinase: Refolding and Reactivation Following Denaturation in Guanidine Hydrochloride.  Int. J. Biochem.,  Vol. 13, 1981, pp 71 - 81.
  2. Brent W. Winston and Nancy E. Henderson.  Seasonal Changes in the Morphology of the Thyroid Gland of a Hibernator, Spermophilus richardsoni.  Can. J. Zool.   Vol. 59 (6), 1981, pp 1022 -31.
  3. Brent W. Winston, Carol A. Lange-Carter, Anne M. Gardner, Gary L. Johnson and David W. H. Riches.  TNFalpha Rapidly Activates the Mitogen-activated Protein Kinase (MAPK) Cascade in a MAPK kinase kinase-dependent, c-Raf-1-Independent Fashion in Mouse Macrophages. Proc. Natl. Acad. Sci. U S A., 1995, Vol. 92, pp1614-1618.
  4. Thierry Fournier, David W. H. Riches, Brent W. Winston, David M. Rose, Scott K. Young, Paul W. Noble, Fiona R. Lake, and Peter M. Henson. Divergence in Macrophage Insulin-like Growth Factor-I (IGF-I) Synthesis Induced by TNFyy and Prostaglandin E2. J. Immunol., 1995, Vol. 155, pp 2123-2133.
  5. Brent W. Winston and David W. H. Riches. Activation of p42mapk/erk2 Following Engagement of Tumor Necrosis Factor Receptor CD120a (p55) in Mouse Macrophages. J. Immunol., 1995, Vol. 15, pp 1525-1533.
  6. Brent W. Winston and David W. H. Riches. Preferential Involvement of MEK1 in the TNF alpha- induced  activation of p42mapk/erk2 in mouse macrophages. J.  Biol. Chem., 1995, Vol 270 (46), pp 27391- 27394.
  7. Natalie J. Avdi, Brent W. Winston, Scott K. Young, Gary L. Johnson and G. Scott Worthen. Activation of MEKK by fMLP in Human Neutrophils. Mapping Pathways for MAP Kinase Activation. J. Biol.  Chem., 1996, Vol 271 (52), pp 33598-33606.
  8. David W. H. Riches, Edward D. Chan, and Brent W. Winston.  TNF alpha-Induced Regulation and Signalling in Macrophages.  Immunobiology, 1996, 195, pp 477-490.
  9. David M. Rose, Brent W. Winston, Edward D. Chan, David W. H. Riches, Par Gerwins, Gary L. Johnson, and Peter M. Henson. Fc gamma-Receptor Cross Linking Activates p42, p38, and JNK/SAPK Mitogen-activated Protein Kinases in Murine Macrophages: Role for p42MAPK in Fcy Receptor-stimulated TNFalpha Synthesis. J. Immunol., 1997, Vol. 158 (7), pp 3433-3438.
  10. Brent W. Winston, Edward D.Chan, Gary L. Johnson, and David W.H. Riches. Activation of p38mapk, MKK3, and MKK4 by TNFalpha in Mouse Bone Marrow- derived Macrophages.  J. Immunol.,1997, Vol. 159(9), pp 4491-4497.
  11. Rose, D. M., B. W. Winston, E.D. Chan, D.W.H. Riches, P.M. Henson. IFNy and TGF beta Modulate the Activation of Mitogen-activated Protein Kinases and TNF apha Production Induced by Fc gamma-receptor Stimulation in Murine Macrophages.  Biochem. Biophys. Res. Commun., 1997, Vol 238(1), pp 256-260.
  12. Edward D. Chan, Brent W. Winston, Linda K. Remigio, Murry W. Wynes, and David W.H. Riches.     Preferential Activation of the p46 Isoform of JNK/SAPK in Mouse Macrophages by TNF alpha.  Proc.  Natl. Acad. Sci. U.S.A., 1997,Vol. 94(24):13169-13174.
  13. D. W. H. Riches, E. D. Chan, E. A. Zahradka, B. W. Winston, L. K. Remigio, and F.  R. Lake. Cooperative Signaling by TNF Receptors CD120a (p55) and CD120b (p75) in the Expression of Nitric oxide and iNOS by Mouse Macrophages. J. Biol. Chem, 1998, Vol 273 (35), pp 22800-22806.
  14. Chan, B. W. Winston, S-t. Uh, M. W. Wynes, D. M. Rose and D. W. H. Riches. Evaluation of the Role of Mitogen-activated Protein Kinases in the Expression of iNOS by IFN gamma and TNF alpha in Mouse  Macrophages. J. Immunol., 1999, Vol. 162:415-422.
  15. E. D. Chan, B. W. Winston, S. T. Uh, L. K. Remigio, and D. W. Riches. Systematic evaluation of the  mitogen-activated protein kinases in the induction of iNOS by TNF alpha and IFN gamma. Chest, 1999, 116(1 Suppl), pp 91S-92S. 
  16. Brent W. Winston, Peter M. Krein, Connie Mowat and Yong Huang. Cytokine-induced Macrophage  Differentiation: A Tale of 2 genes. Clin. Invest.  Med., 1999, Vol. 22 (6): 236-255.
  17. Yong Huang, Tiliang Deng and Brent W. Winston. Characterization of hPRP4 Kinase Activation: Potential Role in Signaling. Biochem. Biophys. Res. Commun., 2000, 271(2), pp 456-463.
  18. Peter M. Krein,Yong Huang and Brent W. Winston.  Growth Factor regulation and Manipulation in wound repair:  to scar or not to scar, that is the question. Expert. Opin. Ther. Patents, 2001, Vol. 11(7):1065-1079.
  19. David Zygun, Ian Anderson, Kevin Laupland, Andreas Kramer, Christopher Doig and Brent W. Winston.    Update in Critical Care Medicine in the New Millennium. Annals  RCSPC, 2001, Vol. 34(5): 297-301.
  20. Yong Huang, Peter M. Krein, and Brent W. Winston.  Characterization of IFN gamma Regulation of the Complement Factor B Gene in Macrophages. Eur. J. Immunol.,  2001, Vol. 31:3676-3686.
  21. Peter M. Krein and Brent W. Winston.  Roles for Insulin-like Growth Factor I (IGF-I) and Transforming Growth Factor-beta (TGF-beta) in Fibrotic Lung Disease.  Chest, 2002, 122(6):289S-293S.
  22. Yong Huang, Peter M. Krein, Daniel Muruve and Brent W. Winston.  Complement Factor B Gene Regulation: Synergistic effects of TNF alpha and IFN gamma in macrophages.  J. Immunol., 2002, Vol. 169:2627-2635.
  23. Peter M. Krein, Peter Sabatini, William Tinmouth, Francis Green, and Brent Winston.  Localization of IGF-I in Lung Tissues of Patients with Fibroproliferative ARDS.  Am. J.  Resp. Crit. Care Med., 2003, Vol. 167(1):83-90.
  24. Shigeki Tsutsui, Jurgen Schnermann, Farshid Noorbakhsh, V. Wee Yong, Brent W. Winston, Kenneth Warren, Christopher Power.  Adenosine AI receptor-regulated neuroinflammation in a model of multiple sclerosis: alleviation of disease by caffeine. Journal of Neuroscience, 2004, Vol. 24:1521-1529.
  25. S. Karmali, KB Laupland, R Harrop, C Findlay, AW Kirkpatrick, BW Winston, JB Kortbeek, L Crowshoe and SM Hameed.  Epidemiology of severe trauma among status Aboriginal Canadians: a population-based study.  Canadian Medical Association Journal, 2005 172(8):1007-1011.
  26. Qiang Liu, Lindsay R. White, Sharon A. Clark, Daniel J. Heffner, Brent W. Winston, Lee Anne Tibbles and Daniel A. Muruve. Akt/Protein Kinase B Activation by Adenovirus  Vectors Contributes to NFkappaB-Dependent CXCL10 Expression.  J Virology, 2005 79(23):14507-14515.
  27. Ai Ni, Rakesh C. Arora and Brent W. Winston. Insulin-like Growth Factors.  In Encyclopedia of Respiratory Medicine.  Editors: Geoffrey J. Laurent and Steven D Shapiro.  Elsevier Ltd. Oxford, UK.  2006.
  28. Deirdre Church, Sameer Elsayed, Owen Reid, Brent Winstonand Robert Lindsay. Burn Wound Infections. Clinical Microbiology Reviews.  2006, 19(2):403-434.
  29. Graciela Andonegui, Kim Goring, Dan Liu, Donna-Marie McCafferty and Brent W. Winston. Characterization of S. pneumoniae pneumonia-induced multiple organ dysfunction syndrome; an experimental mouse model of gram-positive sepsis. Shock, 2009, 31(4):423-428.
  30. Kim Goring, Yong Huang, Connie Mowat, Caroline Leger, Teik-How Lim, Raza Zaheer, Dereck Mok, Lee Anne Tibbles, David Zygun and Brent W. Winston.  Mechanisms of human complement factor B induction in sepsis and inhibition by activated protein C. Amer J Physiol – Cell Physiol, 2009, 296(5):C1140-1150.
  31. Caroline Léger, Ai Ni, Graciela Andonegui, Josée Wong, Connie Mowat and Brent W. Winston. Adenovirus-mediated gene transfer of IGF-I to mouse lungs induced prolonged inflammation but no fibroproliferation. Amer J Physiol – Lung Cellular and Molecular Physiology, 2010, 298(4):L492-500.
  32. Graciela Andonegui, Ai Ni, Caroline Léger, Margaret Kelly, Josée Wong, Ali Jalloul and Brent W. Winston. Expression of IGF-I followed by TGF-1(active) induces synergistic pulmonary fibroproliferation in vivo. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 1;303(9):L788-98.
  33. Lalu M.M. ; McIntyre, L.; Pugliese, C.; Fergusson, D.; Winston, B.W.,  Marshall, J.C.; Granton, J.; Stewart D.J.; and the Canadian Critical Care Trials Group. Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): a systematic review of clinical trials. PLoS One. 2012;7(10):e47559.
  34. Deirdre Church, Ingrid Slaba, Brent Winstonand Robert Lindsay. Burn Wound Infections. In The Prokaryotes:The Prokaryotic Biology and Symbiotic Associations, 4th Edition. Eugene Rosenberg Editor. (Published 2013 on line: www.springerreference.com).
  35. Beata Mickiewicz, Hans J Vogel, Hector R Wong, and Brent W. Winston. Metabolic profiling of serum samples by 1H NMR spectroscopy as a novel approach for early prognostic evaluation of pediatric septic shock and its mortality. Am. J. Respir. Crit. Care Med. rccm.201209-1726OCFirst published online March 7, 2013 as doi:10.1164/rccm.201209-1726OC
  36. Beata Mickiewicz; Gavin E. Duggan; Brent W. Winston; Christopher Doig; Paul Kubes; Hans J. Vogel for the Alberta Sepsis Network (ASN).  Metabolic profiling of serum samples by 1H NMR spectroscopy as a potential diagnostic approach for septic shock. Crit Care Med. First published online Dec 23, 2013. [Epub ahead of print]. Print version, CCM, 2014, 42(5):1140-1149.
  37. Mohammad M. Banoei, Sarah J. Donnelly, Beata Mickiewicz, Aalim Weljie, Hans J. Vogel and Brent W. Winston. Metabolomics in critical care medicine, a new approach to biomarker discovery. Clinical and Investigative Medicine, 37(6), 2014, E363-376.
  38. Graciela Andonegui, Peter M. Krein, Connie Mowat, Ron Brisebois, Christopher Doig, Francis Green, Caroline Léger and Brent W. Winston. Enhanced production of IGF-I in the lungs of fibroproliferative ARDS patients. Physiol Rep, 2(11), 2014, e12197, doi: 10.14814/phy2.12197.
  39. Beata Mickiewicz, Patrick Tam, Craig N. Jenne, Caroline Leger, Josee Wong, Brent W. Winston, Christopher Doig, Paul Kubes and Hans J. Vogel for the Alberta Sepsis Network (ASN). Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit. Critical Care 2015, 19 :11 (15 January 2015). doi:10.1186/s13054-014-0729-0.
  40. Mehdi Mirsaeidi, Mohammad Mehdi Banoei, Caleb K. Nienow, Taimur Abassi, Anoushirvan Hakim, Dean Schraufnagel, Brent W. Winston, Nadera Sweiss, Robert Baughman, Joe G.N. Garcia, Roberto Machado.   Plasma metabolomics profile in fibrosing pulmonary sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2016 Mar 29;33(1):29-38.
  41. Mehdi Mirsaeidi, Mehdi Mohammad Banoei, Brent W. Winston, Dean E. Schraufnagel. Metabolomics: Applications and Promise in Mycobacterial Disease. Ann Am Thorac Soc. 2015 Sep;12(9):1278-87. doi: 10.1513/AnnalsATS.201505-279PS.
  42. Beata Mickiewicz, Graham Thompson, Jaime Blackwood, Craig N Jenne, Brent W Winston, Hans J Vogel, and Ari R Joffe for the Alberta Sepsis Network. Development of metabolic and inflammatory mediator biomarker phenotyping for early diagnosis and triage of pediatric sepsis. Crit Care. 2015 Sep 9;19:320. doi: 10.1186/s13054-015-1026-2.
  43. A A Mourad, M M Banoei, S J Donnelly, and B W Winston. Predicting the mortality of pneumonia-induced direct lung injury using serum metabolomics. Extended abstract, Journal of Undergraduate Research in Alberta (JURA)­, Vol. 5, 2015.
  44. Yipp, BG, Winston, BW. Sepsis without SIRS is still sepsis. Ann Transl Med, 2015. doi: 10.3978/ j.issn.2305-5839.2015.11.13.
  45. Mirsaeidi M, Banoei MM, Winston BW, Schraufnagel DE. Reply:  Metabolomics and Mycobacterial Disease:  Don't Forget the Bioinformatics. Ann Am Thorac Soc. 2016 Jan;13(1):142-3. doi: 10.1513/AnnalsATS.201510-711LE.
  46. Manoj M. Lalu, Katrina Sullivan, Shirley  Mei, David Moher, Alex Strauss, Dean A. Fergusson, Duncan J. Stewart, Mazen Jazi, Malcolm MacLeod, Brent Winston, John Marshall, Brian Hutton, Keith Walley, Lauralyn McIntyreon behalf of the Canadian Critical Care Translational Biology Group. Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analysis prior to initiating a first-in-human trial. eLife, November 15 ,2016. Doi:10.7554/eLife.17850
  47. Mohammad M. Banoei, Hans J. Vogel, Aalim M Weljie, Anand Kumar, Sachin Yende, Derek C Angus, Brent W. Winston and the Canadian Critical Care Translational BiologyGroup (CCCTBG). Plasma metabolomics for the diagnosis and prognosis of H1N1 influenza pneumonia. Critical Care, 2017, 21:97. Doi:10.1186/s13054-017-1672-7.
  48. Kinetics of Serological Responses in Critically Ill Patients Hospitalized With 2009 Pandemic Influenza A(H1N1) Virus Infection in Canada, 2009-2011. Rolfes MA1, Gross FL1,2, Flannery  B1, Meyers AFA3,4,5, Luo M3, Bastien N3, Fowler RA6, Katz JM1, Levine MZ1, Kumar A7,8, Uyeki TM1; CSIS and ROSII Study Groups. J Infect Dis. 2018 Mar 13;217(7):1078-1088. doi: 10.1093/infdis/jiy013. Brent W. Winston was part of the study group.
  49. Michelle Eckerle, Lilliam Ambroggio, Michael Puskarich, Brent Winston, Alan E. Jones, Theodore J. Standiford and Kathleen A. Stringer. Metabolomics as a Driver in Advancing Precision Medicine in Sepsis. Pharmacotherapy, April 3, 2017. Doi: 10.1002/phar.1974.
  50. Russell Bowler, Mike Fessler, Matt Foster, Rachel Kelly, Angela Rogers, Kathleen Stringer, Jessica Lasky-Su, Brent W. Winston and Chris Wendt. An Official American Thoracic Society Workshop Report: New Strategies and Challenges in Lung Proteomics and Metabolomics.  Ann Am Thorac Soc Vol 14, No 12, pp 1721–1743, Dec 2017.
  51. Lauralyn A. McIntyre, Duncan J. Stewart, Shirley H. J. Mei, David Courtman, Irene Watpool, John Granton, John Marshall, Claudia dos Santos, Keith R. Walley, Brent W. Winston, Dean A. Fergusson, For the Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical. Am J Respir Crit Care Med. 2018 Feb 1;197(3):337-347. doi: 10.1164/rccm.201705-1006OC.
  52. Colin Casault, M.D.; Abdul-Aziz Al-Sultan, M.D.; Mohammad Banoei, DVM, MSc; Philippe Couillard, M.D.; Andreas Kramer, M.D. M.Sc.; Brent Winston, M.D.  Cytokine Responses in Severe Traumatic Brain Injury: Where there is smoke, is there fire? Neurocrit Care. 2018 Mar 22. doi: 10.1007/s12028-018-0522-z. [Epub ahead of print].
  53. Mustafa Al-Saiedy, Lasantha Gnasekara, Francis Green, Ryan Pratt, Andrea Chiu, Ailian Yang, John Dennis, Cora Pieron, Candice Bjornson, Brent Winston and Matthias Amrein. Surfactant Dysfunction in ARDS and Bronchiolitis is repaired with Cyclodextrins. Mil Med. 2018 Mar 1;183(suppl_1):207-215. doi: 10.1093/milmed/usx204.
  54. Mohammad M. Banoei, Colin Casault, Sayed Metlwaly, and Brent W. Winston. Metabolomics and biomarker discovery in Traumatic Brain Injury. Journal of Neurotrauma, Volume: 35 Issue 16: August 15, 2018; [Epub ahead of print] Mar 27. doi: 10.1089/neu.2017.5326.
  55. Graciela Andonegui, Erin L. Zelinski, Courtney L. Schubert, Derrice Knight, Laura Craig, Brent W. Winston, Simon C. Spanswick,Björn Petri, Craig Jenne, Janice C. Sutherland, Rita Nguyen, Natalie Jayawardena, Margaret M. Kelly, Christopher J. Doig, Robert J. Sutherland, Paul Kubes. Targeting inflammatory monocytes in sepsis-associated encephalopathy and long-term cognitive impairment. JCI Insight. 2018;3(9):e99364. https://doi.org/10.1172/jci.insight.99364.
  56. Sayed Metwaly, Andreanne Cote, Sarah J. Donnelly, Mohammad M. Banoei, Ahmed I. Mourad, and Brent W. Winston. Evolution of ARDS Biomarkers: Will Metabolomics be the answer? Am J Physiol Lung Cell Mol Physiol. 2018 Jun 28. doi: 10.1152/ajplung.00074.2018. [Epub ahead of print]
  57. MMP Faria, BW Winston, MG Surette and JM Conly. Bacterial DNA patterns identified using paired-end Illumina sequencing of 16S rRNA genes from whole blood samples of septic patients in the emergency room and intensive care unit. BMC Microbiology, BMC Microbiology (2018) 18:79. https://doi.org/10.1186/s12866-018-1211-y.
  58. Beata Mickiewicz, Graham Thompson, Jaime Blackwood, Craig N Jenne, Brent W. Winston, Hans J. Vogel, Ari R. Joffe. Biomarker Phenotyping for Early Diagnosis and Triage of Sepsis to the Pediatric Intensive Care Unit. Sci Rep. 2018 Nov 9;8(1):16606. doi: 10.1038/s41598-018-35000-7.
  59. Kenny Schlosser, Jiapey Wang, Irene Watpool, Duncan J. Stewart , Lauralyn A. McIntyre, John Granton, John Marshall, Claudia dos Santos, Keith R. Walley, Brent W. Winston, Dean A. Fergusson, Shirley H. J. Mei and the Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine levels in Septic Shock Patients. Crit Care Med. 2019 Jul;47(7):918-925. doi: 10.1097/CCM.0000000000003657.         
  60. P. C. Liaw*, A. Fox-Robichaud*, E. McDonald, D. J. Dwivedi, K. L. Liaw, L. Pepler, T. J. Gould, M. Xu, M., N. Zytaruk, L. McIntyre, J. Marshall, J. Tsang, P. M. Dodek, B. W. Winston, C. Martin, D. Fraser, J. I. Weitz, F. Lellouche, and D.J. Cook on behalf of the Canadian Critical Care Translational Biology Group and the Canadian Critical Care Trials Group. Mortality Risk Profiles for Sepsis: A Novel Longitudinal and Multivariable Approach. Crit Care Expl 2019; XXX:e0032. DOI: 10.1097/CCE.0000000000000032.
  61. Mohammad Mehdi Banoei, Isabella Iupe, Reza Dowlatabadi Bazaz, Michael Campos, Hans J Vogel, Brent W. Winston and Mehdi Mirsaeidi. Metabolomic and metallomic profile differences between Veterans and Civilians with Pulmonary Sarcoidosis. Sci Rep 9, 19584 (2019) doi:10.1038/s41598-019-56174-8.
  62. Mary Thompson, Shirley Mei, Dianna Wolfe, Josée Champagne, Dean Fergusson, Duncan Stewart, Katrina Sullivan, Emily Doxtator, Manoj Lalu, Shane W English, John Granton, Brian Hutton, John Marshall, Alies Maybee, Keith Walley, Brent Winston, and Lauralyn McIntyre. Cell Therapy with Mesenchymal Stromal Cells Continues to Appear Safe: An Updated Systematic Review and Meta-Analysis. EClinicalMedicine 19 (2019), 100249  doi: 10.1016/j.eclinm.2019.100249. eCollection 2020 Feb.
  63. Sayed M. Metwaly and Brent W. Winston. Systems Biology ARDS Research with a Focus on Metabolomics. Metabolites 2020, 10, 207; doi:10.3390/metabo10050207.
  64. Mohammad M. Banoei, Hans J. Vogel, Aalim M. Weljie, Sachin Yende, Derek C. Angus and Brent W. Winston. Plasma lipid profiling for the prognosis of 90-day mortality, in-hospital mortality, ICU admission and severity in bacterial community acquired pneumonia (CAP). Crit Care 24, 461 (2020). https://doi.org/10.1186/s13054-020-03147-3.
  65. Ryan McGinn, Duncan J. Stewart, Dean Fergusson, Arnold Kristof, Carly C. Barron, Lauralyn McIntyre, Dawn Stacey, Bernard Thebaud, Mark Liepmann, Aurore Dodelet-Devillers, Haibo Zhang, Richard Renlund, Elliot Lilley, Greg Downey, Earl Brown, Lucie Cote, Claudia Dos Santos, Alison Fox-Robichaud, Sabah Hussain, Jonathan Laffey, Mingyiao Liu, Jenna MacNeil, Holly Orlando, Salman Qureshi, Patricia Turner, Brent W. Winston and Manoj M. Lalu,  on behalf of the Canadian Critical Care Translational Biology Group. "Surrogate humane endpoints in small animal models of acute lung injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians". Critical Care Medicine, 2021, 49(2):311-23. DOI: 10.1097/CCM.000000000000473
  66. Asher A Mendelson; Casey Lansdell; Alison E Fox-Robichaud; Patricia Liaw; Jaskirat Arora; Jean-François Cailhier; Gedminas Cepinskas; Emmanuel Charbonney; Claudia dos Santos; Dhruva Dwivedi; Christopher G Ellis; Dean Fergusson; Kirsten Fiest; Sean E Gill; Kathryn Hendrick; Victoria T Hunniford; Paulina M Kowalewska; Karla Krewulak; Christian Lehmann; Kimberly Macala; John C Marshall; Laura Mawdsley; Braedon McDonald; Ellen McDonald; Sarah K Medeiros; Valdirene S Muniz; Marcin Osuchowski; Justin Presseau; Neha Sharma; Sahar Sohrabipour; Janet Sunohara-Neilson; Gloria Vázquez-Grande; Ruud AW Veldhuizen; Donald Welsh; Brent W Winston; Ryan Zarychanski; Haibo Zhang; Juan Zhou; Manoj Lalu. “National Preclinical Sepsis Platform: Developing a framework for accelerating innovation in Canadian sepsis research.” Intensive Care Medicine Experimental, In Press.
  67. Lee T, Cau A, Cheng MP, Levin A, Lee TC, Vinh DC, Lamontagne F, Singer J, Walley, KR, Murthy S, Patrick, D, Rewa O, Winston BW, Marshall, J, Boyd, J, Tran K  Luther, JM, Opal, S,Kalil A, McCuloh, R, Russell, JA on behalf of ARBs Corona. Angiotensin receptor blockers and angiotensin converting enzyme inhibitors in covid-19– meta-analysis/meta-regression adjusted for confounding factors. Submitted to The Canadian J Cardiology Open, 2021 in press. 2021 Apr 6.doi: 10.1016/j.cjco.2021.03.001. Online ahead of print.
  68. Brittney N. V. Scott; Andreas H. Kramer; Rita Nguyen; Connie H.Y. Wong; Craig N. Jenne; Stacy Ruddell; Josee Wong; Mandy Tse; Brent W Winston; Andrea Soo; Christopher J. Doig; David A. Zygun; Paul Kubes. "Evaluation of the relationship between iNKT cells and systemic cytokine profiles of critically ill patients with neurological injury". Neurocritical Care, 2021, Neurocrit Care (2021). https://doi.org/10.1007/s12028-021-01234-z
  69. Sayed Metwaly, Sarah J. Donnelly, Mohammad M. Banoei, Ahmed I. Mourad, Hans J. Vogel, Oliver Fiehn, Brent W Winston on behalf of the Canadian Critical Care Translational Biology Group (CCCTBG). “ARDS Metabolic Fingerprints: Characterization, Benchmarking and Potential Mechanistic Interpretation.” Am J Physiol Lung Cell Mol Physiol. 2021 May 5, 321: L79–L90.  doi, 10.1152/ajplung.00077.2021.
  70. Cau, Alessandro; Cheng, Matthew; Lee, Terry; Levin, Adeera; Lee, Todd; Vinh, Donald; Lamontagne, François; Singer, Joel ; Walley, Keith; Murthy, Srinivas; Patrick, David; Rewa, Oleksa; Winston, Brent; Marshall, John; Boyd, John; Russell, James. "Acute Kidney Injury and Renal Replacement Therapy in COVID-19 Versus Other Respiratory Viruses – A Systematic Review and Meta-Analysis." Accepted for publication in the Canadian Journal of Kidney Health and Disease, 2021.
  71. Kevin Burns, Matthew Cheng, Todd Lee, Allison McGeer, David Sweet, Karen Tran, Terry Lee, Srinivas Murthy, John Boyd, Joel Singer, Keith Walley, David Patrick, Francois Lamontagne, John C. Marshall, Gregory Haljan, Robert Fowler, Brent Winston, and James Russell. Sustained Dysregulation of the Plasma Renin-Angiotensin System in Acute COVID-19. Research Square, 2021. Preprint before publication. doi, 10.21203/rs.3.rs-125380/v1.
  72. Mohammed, Yassene; Goodlett, David; Cheng, Matthew; Vinh, Donald; Lee, Todd; Mcgeer, Allison; Sweet, David; Tran, Karen; Lee, Terry; Murthy, Srinivas; Boyd, John; Singer, Joel; Walley, Keith; Patrick, David; Quan, Curtis; Ismail, Sara; Amar, Laetitia; Pal, Aditya; Bassawon, Rayhaan; Fesdekjian, Lara; Gou, Karine; Lamontagne, Francois; Marshall, John; Haljan, Greg; Fowler, Robert; Winston, Brent; Russell, James for ARBs Corona I. "Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19". Accepted for publication in The Journal of Proteome Research, 2021.
  73. Meng Wang, Terry Lee, James A. Russell and Mari L. DeMarco (for the ARBs CORONA I investigators). Contributing authors: Taylor D. Pobran, Terry Lee, Matthew P. Cheng, Karen Tran, David Sweet, John Marshall, Arthur S. Slutsky, Srinivas Murthy, Joel Singer, David M. Patrick, Todd C. Lee, John H. Boyd, Keith R. Walley, Francois Lamontagne, Robert Fowler, Brent W. Winston, Greg Haljan, Donald C. Vinh, Alison McGeer, David Maslove, Puneet Mann, Kathryn Donohoe, Geraldine Hernandez, Anita Palepu. Early increases in anti-SARS-CoV-2 antibody isotypes associated with organ dysfunction and mortality in patients hospitalized with COVID-19. Intensive Care Med. 2022 May;48(5):616-618. doi: 10.1007/s00134-022-06662-9. Epub 2022 Apr 2.
  74. Sarah A. Angus, William R. Henderson, Mohammad M. Banoei, Yannick Molgat-Seon, Carli M. Peters, Hannah R. Parmar, Donald E. G. Griesdale, Mypinder Sekhon, A. William Sheel, Brent W. Winston, and Paolo B. Dominelli. Therapeutic Hypothermia Attenuates Physiologic, Histologic and Metabolomic Markers of Injury in a Porcine Model of Acute Respiratory Distress Syndrome. Accepted for publication in Physiological Reports, 2022, 10, e15286. https://doi.org/10.14814/ phy2.15286
  75. Terry Lee, PhD, Matthew Cheng, MD, Todd C. Lee, MD, Karen Tran, MD, Brent W. Winston, MD, David Sweet, MD, John H. Boyd, MD, Keith R. Walley, MD, Greg Haljan, MD,  Alison Mcgeer, MD, Francois Lamontagne, MD, Robert Fowler, MD, Natalie Farshait, David Maslove, MD, Joel Singer, PhD, David M. Patrick, MD, John Marshall, MD, Kevin D. Burns, MD, Srinivas Murthy, MD, Puneet K. Mann MSc, Geraldine Hernandez, BSc, Kathryn Donohoe BSc, James A. Russell, MD, For ARBs Corona I.  Organ dysfunction and death in patients admitted to hospital with COVID-19 in pandemic waves 1 to 3 in British Columbia, Ontario and Quebec, Canada: a cohort study. CMAJ Open 2022 April 19. DOI:10.9778/cmajo.20210216
  76. Gnevieve L. Y. Rocheleau, Tery Lee, Yassene Mohammed, David Goodlett, Kevin Burns, Matthew P. Cheng, Karen Tran, David Sweet, John Marshall, Arthur Slutsky, Srinivas Murthy, Joel Singer, David M. Patrick, Du Bin, Zhiyong Peng, Todd C. Lee, John H. Boyd, Keith R. Walley, Francois Lamontagne, Robert Fowler, Brent W. Winston, Greg Haljan, Donald C. Vinh, Alison McGeer, Nataly Farshait, David Maslove, Santiago Perez Patrigeon, Puneet Mann, Kathryn Donohoe, GeraldineHernandez, James A. Russell, for ARBs CORONA I Investigators. RAS Pathway Therapeutics Associated with Improved Outcomes in Males Hospitalized with COVID-19. Crit Care Med. 2022 May 19. doi: 10.1097/CCM.0000000000005589. Online ahead of print. PMID: 35607951.
  77. Mohammad Mehdi Banoei*, Etienne Mah*, Adnan Mansoor, Douglas Stewart, Brent W. Winston, Hamid R. Habibi, Meer-Taher Shabani-Rad. NMR-based metabolomic profiling can differentiate follicular lymphoma from benign lymph node tissues and may be predictive of outcome. Scientific Reports 2022, 12:8294. https://doi.org/10.1038/s41598-022-12445-5 *shared first-author.
  78. Cairncross, Molly; Gindwani, Hiresh; Egbert, Anna Rita; Torres, Ivan; Hutchison, Jamie; Dams-O'Connor, Kristen; Panenka, William; Brubacher, Jeff; Meddings, Louise; Kwan, Lexynn; Yeates, Keith O; Green, Robin; Barlow, Karen; Esser, Michael; Winston, Brent; Wellington, Cheryl; Walley, Keith ; Carrion, Prescilla; Doan, Quynh; Stukas, Sophie; Vercauteren, Susan; Murthy, Srinivas; Aquino, Angela; Lorelei, Audas; Clarke, David; Davis, Adrienne; Colantonio, Angela; Wheeler, Anne; Guerguerian, Anne-Marie; Gilfoyle, Elaine; Hazrati, Lili-Naz; Scratch, Shannon E.; Sinopoli, Katia; Wilson, Elisa; Khosroawshahi, Arash; Granofsky, Grace; Fernandes, Leanne; Farrell, Catherine; Lacroix, Jacques; French, Mary-ellen; Poirier, Josée and Silverberg, Noah D. Criterion validity of the Brief Test of Adult Cognition by Telephone (BTACT) for mild traumatic brain injury.  In Press, Brain Injury, March 2022.
  79. Nicole Sarden, Erwan Pernet, Kyle Potts, Brent W. Winston, Josee Wong, Amy Bromley, Brendan D. Snarr, Amanda Z. Zucoloto, Carlos H. Hiroki, Mortaza F. Hassanabad, Raquel Farias, Angela P. Nguyen, Braedon McDonald, Donald C. Sheppard, Douglas J. Mahoney, Maziar Divangahi, Bryan G. Yipp. A B1a–natural IgG–neutrophil axis is impaired in viral- and steroid-associated aspergillosis. Science Translational Medicine, 7 Dec 2022, Vol 14, Issue 674. DOI: 10.1126/scitranslmed.abq6682.
  80. Terry Lee, PhD, Matthew P. Cheng, MD, Donald C. Vinh, Todd C. Lee, MD, Karen C. Tran, MD, Brent W. Winston, MD, David Sweet, MD, John H. Boyd, MD, Keith R. Walley, MD, Greg Haljan, MD, Allison Mcgeer, MD, Francois Lamontagne, MD, Robert Fowler, MD, David M. Maslove, MD, Joel Singer, PhD, David M. Patrick, MD, John C. Marshall, MD, Kevin D. Burns, MD, Srinivas Murthy, MD, Puneet K. Mann, MSc, Geraldine Hernandez, BSc, Kathryn Donohoe, BSc, James A. Russell, MD, For Arbs Corona 1. Outcomes and characteristics of Omicron wave patients hospitalized for COVID-19 in British Columbia, Ontario and Quebec, Canada: A cohort study comparing patients by vaccination status and with prior waves. Submitted to CMAJ Open, Accepted for publication, 2023.
  81. Mohammad M. Banoei, Chel Hee Lee, James Hutchison, William Panenka,  David A Wishart, Brent W. Winston, on behalf of the Canadian Biobank and Database for Traumatic Brain Injury (CanTBI) investigators, the Canadian Critical Care Translational Biology Group (CCCTBG) and the Canadian Traumatic Brain Injury Research and Clinical Network (CTRC). Metabolomic profiles in serum predict global functional neurological outcome and death at 3 and 12 months following severe traumatic brain injury. Critical Care, 2023, 27:295. https://doi.org/10.1186/s13054-023-04573-9.
  82. Riley Fedorak, Chel Hee Lee, Mohammad Banoei and Brent W. Winston. Metabolomics in severe traumatic brain injury: a scoping review. BMC Neuroscience (2023) 24:54.  https://doi.org/10.1186/s12868-023-00824-1
  83. Christine Hum, Usama Tahir, Shirley Mei, Josee Champagne, Dean Fergusson, Manoj Lalu, Duncan Stewart, Keith Walley, John Marshal, Brent Winston, Claudia dos Santos, Chintan Dave and Lauralyn McIntyre for the Canadian Critical Care Translational Biology Group. Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Pre-clinical Models of Sepsis: A Systematic Review and Meta-Analysis. Stem Cells Translational Medicine, 2023, Under revision.
  84. Mohammad M. Banoei, Lauralyn A. McIntyre, Duncan J. Stewart, Shirley H. J. Mei,  David Courtman, Irene Watpool, John Granton,  John Marshall, Claudia dos Santos, Keith R. Walley, Kenny Schlosser, Dean A. Fergusson, and Brent W. Winston, For the Canadian Critical Care Trials Group and the Canadian Critical Care Translational Biology Group. Metabolomics Analysis of MSC Therapy in A Phase I Clinical Trial of Septic Shock. Metabolites 2023, 13, 1142. https://doi.org/10.3390/metabo13111142.
  85. Mohammed, Yassene; Tran, Karen; Carlsten, Chris; Ryerson, Christopher; Wong, Alyson; Lee, Terry; Cheng, Matthew; Vinh, Donald; Lee, Todd; Winston, Brent; Sweet, David; Boyd, John; Walley, Keith; Haljan, Greg; McGeer, Allison; Lamontagne, Francois; Fowler, Robert; Maslove, David; Singer, Joel; Patrick, David; Marshall, John; Murthy, Srinivas; Jain, Fagun; Borchers, Christoph; Goodlett, David; Levin, Adeera; Russell, James. Proteomics Evolution from Acute to Post-Covid-19 Condition. Journal of Proteome Research. Accepted Nov 13, 2023. https://doi.org/10.1021/acs.jproteome.3c00324
  86. Andréanne Côté*, Chel Hee Lee*, Sayed M. Metwaly,, Christopher J. Doig, Graciela Andonegui, Bryan G. Yipp, Ken Parhar, and Brent Winston. Endotyping in ARDS: One Step Forward in Precision Medicine.  Eur J Med Res 2024 May 14;29(1):284.doi: 10.1186/s40001-024-01876-7. 
  87. Chel Hee Lee, Mohammad M. Banoei, Mariam Ansari, Matthew P. Cheng, Francois Lamontagne, Donald Griesdale, David E. Lasry, Koray Demir, Vinay Dhingra, Karen C. Tran, Terry Lee, Kevin Burns, David Sweet, John Marshall, Arthur Slutsky, Srinivas Murthy, Joel Singer, David M. Patrick, Todd C. Lee, John H. Boyd, Keith R. Walley, Robert Fowler, Greg Haljan, Donald C. Vinh, Alison Mcgeer, David Maslove, Puneet Mann, Kathryn Donohoe, Geraldine Hernandez, Genevieve Rocheleau, Uriel Trahtemberg, Anand Kumar, Claudia dos Santos, Andrew Baker, James A. Russell, and Brent W. Winston for the *ARBs CORONA I Investigators. Metabolomics analysis of different infectious causes of ARDS: COVID-19, H1N1, and Bacterial pneumonia. Critical Care, 2024, 28:63. https://doi.org/10.1186/s13054-024-04843-0.
  88. Karen Tran; Pierre Asfar; Matthew Cheng; Julien Demiselle; Joel Singer; Terry Lee; David Sweet; John Boyd; Keith Walley; Greg Haljan; Omar Sharif; Guillaume Geri; Johann Auchabie; Jean-Pierre Quenot; Todd C. Lee; Jennifer Tsang; Ferhat Meziani; Francois Lamontagne; Vincent Dubee; Sigismond Lasocki; Daniel Ovakim; Gordon Wood; Alexis Turgeon-Fournier; Yves Cohen; Eddy Lebas; Marine Goudelin; David Forrest; Alastair Teale; Jean-Paul Mira; Robert Fowler; Nick Daneman; Neil Adhikari; Marie Goussef; Pierre Leroy; Gaetan Plantefeve; Patrick Rispal; Roxane Courtois; Brent Winston; Steve Reynolds; Peter Birks; Boris Bienvenu; Jean-Marc Tadie; Severine Ansart; Jean-Philippe Talarmin; James Russell. "Effects of Losartan on Patients Hospitalized for Acute COVID-19; A Randomized Controlled Trial." Clinical Infectious Diseases, July 10, 2024;, ciae306, https://doi.org/10.1093/cid/ciae306
  89. Greg Haljan, MD, Terry Lee, Ph D, Robert Fowler, MD, Francois Lelouche, MD, Alexis-Turgeon-Fournier, Jennifer Yoon, Jennifer Tsang, MD, Anne Mccarthy, MD, Peter Daley, Matthew P. Cheng, MD, Donald C. Vinh, Todd C. Lee, MD, Karen C. Tran, MD, Francois Lamontagne, MD, Brent W. Winston, MD, David Sweet, MD, John H. Boyd, MD, Keith R. Walley, MD, Allison Mcgeer, MD, David M. Maslove, MD, Joel Singer, Ph D, John C. Marshall, MD, Fagun Jain, and James A. Russell, MD, for CAPTIVATE. Complex Thrombo-Inflammatory Responses Versus Outcomes of Non-Covid-19 Community-Acquired Pneumonia and Covid-19. Journal of Innate immunity, 2024, In Print.