• PSOM is a standardized questionnaire to be completed by the doctor for the affected child. The PSOM is a short neurologic examination evaluating neurological  deficits and function across five domains:
  • Sensorimotor on the right side
  • Sensorimotor on the left side
  • Language production
  • Language comprehension
  • Cognition or behavior
• Each domain is scored according to the level of functioning and the interference on daily life activities (DLA): 0 (normal), 0.5 (mild deficit, normal function), one(moderate deficit, decreased function), or two (severe deficit, missing function).
• The doctor can use this tool to assess the child’s neurological outcome at follow-up visits. 

• Physician Global Assessment evaluates overall disease activity, reversible impairment, and permanent damage of the child.
• This assessment is a 10 centimeter visual analog scale with 0 being no disease activity and 10 being maximum disease activity.
• At SickKids, this is part of standard of care and the PGA is completed at every visit.

• Neurocognitive assessment evaluates a wide range of neuropsychological abilities including overall intellectual ability, language, attention, learning, memory, visual perception, visual-motor skills, executive skills and early academic skills. 
• The assessment typically consists of a standardised battery of tests. Testing is recommended  in all patients with inflammatory brain disease at baseline and then yearly thereafter. 
• This testing is important in identifying neurocognitive deficits and in monitoring progress over time. It helps to identify a child's strengths and weaknesses and guides early rehabilitation to optimize functional outcome.

• The PedsQL is a tool that is used to measure the health-related quality of life (HRQOL) of children affected by chronic diseases (such as CNS vasculitis) and their parents.  It is a 23 item questionnaire that asks about:
  • Physical Functioning (8 items)
  • Emotional Functioning (5 items)
  • Social Functioning (5 items)
  • School Functioning (5 items)
• Three summary scores are then generated, namely a total scale score, physical health summary score, and psychosocial health summary score.

• The SMI-ily is a brief, easily understood, valid, and reliable pediatric quality of life (QOL) scale.  It is used to measure the health-related quality of life (HRQOL) of children affected by chronic diseases (such as CNS vasculitis) and their parents. 
• It has parallel child and parent reports with a 5-faces scale (,  , etc.) for responses.  SMI-ily encompasses 4 domains, namely:
  • Effect of disease on self
  • Limitations related to disease
  • Social impact of disease
  • Burden of disease

There is currently no specific rehabilitation outcome tool validated for use in CNS Vasculitis, mostly in children. Research is currently underway to validate a motor outcome tool for use in CNS Vasculitis patients.  In the meantime, these outcome measures may help clinicians to assess areas of impairment and identify a patient’s rehabilitation needs:

• Task-based observational measure which assesses gross and fine motor skills with sex and age-matched normative values for comparison.
• Short-form version takes approximately 20 minutes to administer.
• More information is available at: http://www.pearsonassessments.com/HAIWEB/Cultures/en-us/Productdetail.htm?Pid=PAa58000 

• Designed to assess changes in gross motor function in patients with Cerebral Palsy and regularly used in patients with acquired brain injury[6].
• More information is available at: https://canchild.ca/en/resources/44-gross-motor-function-measure-gmfm.
• Children’s Orientation and Amnesia Scale (COAT)[7].
• Standardized measures  designed to assess cognitive functioning in children and adolescents with an acquired brain injury.
• Composed of 16 items, the COAT addressed 3 areas of cognitive functioning:  general orientation, temporal orientation, and memory.

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2. Sztajnbok F, et al,.Discrepancy between patient and physician in assessment of global severity in early rheumatoid arthritis. Rheumatology (Oxford, England) 2007;46:141–145
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4. Moorthy, LN, et al. Multicenter validation of a new quality of life measure in pediatric lupus. Arthritis Rheum, 2007. 57 (7): p. 1165-73.
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6. Russell D RP, et al,. Gross Motor Function Measure. 2nd ed. Toronto, Ontario, Canada; 1993.
7. Iverson GL, Iverson AM, Barton EA. The Children’s Orientation and Amnesia Test: Education status is a moderator variable in tracking recovery from TBI. Brain Injury 1994; 8(8): 685-688.