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Applied Spatial Omics Centre

State-of-the-art technologies to fulfill the needs of translational researchers

About ASOC

The Applied Spatial Omics Centre (ASOC) constitutes the hub of Spatial Transcriptomics/Proteomics and Bioinformatics. ASOC provides advanced genomic technologies and cutting-edge methods to researchers and clinicians at the University of Calgary as well as external academic and industry Scientists. ASOC is organized as a centre within the University of Calgary, Cumming School of Medicine, an interdisciplinary research institute that is driven to the future of medicine. 

Our Mission

We aim to support ground-breaking research in genetics and genomics by integrating advanced technologies. One of the most transformative is the "Spatial Transcriptomics (ST)" revolutionizing biological research in recent years. We provide a hub of expertise in advanced techniques, ensuring the upkeep of ST and accompanying genomic tools alongside comprehensive bioinformatics support. This framework empowers researchers to harness these methodologies efficiently for their scientific breakthroughs.

Spatial Technology User Guildeline

Available services and guidelines for Spatial Transcriptomics

Available Commercial Platforms

A list of the in-house commercial platforms

Bioinformatics Analysis

The Bioinformatics team offers Spatial data analysis

Services

  1. Study design assistance: ASOC provides consultation services, assisting researchers in formulating effective study methodologies suitable for their research objectives.
  2. Technical services for Spatial Omics: With a keen focus on precision and accuracy, ASOC delivers comprehensive analyses of RNA and protein from tissue sections, enabling a deeper understanding of spatial omics.
  3. Histology & Histochemistry: A broad range of histological services for spatial omics analysis are available. 
  4. Sample preparation for Next-Generation Sequencing (NGS): To ensure the integrity of samples, ASOC has rigorous preparation protocols to yield optimal outcomes from NGS platforms.
  5. Bioinformatics analysis: ASOC's Bioinformatics team offers rigorous data QC, analysis, and interpretation of Spatial Omics data into meaningful insights.

Platforms

NanoString

  • GeoMx® Digital Spatial Profiler (DSP)
  • CosMx™Spatial Molecular Imager (SMI)
  • AtoMx™Spatial Informatics Platforms (SIP)

10X Genomics

  • Visium Spatial Gene Expression/CytAssist  
  • Xenium In Situ
  • Chromium Next GEM single cell (Partner with CHGI)