508

Honours Thesis

508 students

Congrats!

Honours thesis students, research supervisors, co-supervisors and preceptors involved in the MDSC 508 capstone course celebrate at the end of the successful oral defenses of the honours theses.  This celebration recognizes the hard work and investment of our students in their thesis research projects and marks the culmination of their undergraduate program. What an accomplishment!

MDSC 508 Honours Thesis Project Titles 2021-2022

The MDSC 508 course is a research-intensive, full-year course taken in the final year of study. The objective is for the student to demonstrate the capacity to conduct a piece of original work in a specific field. 

  1. Promise Adeboye

    Operationalizing and examining 'flourishing' using drected acyclic graphs and longitudinal cohort data from All Our Families: a methodological exploration

  2. Hailey Allen

    Role of NF-κB in the regulation of IL-1β-induced genes in pulmonary epithelial cells

  3. Keaton Banik

    Exploring Bayesian approaches to phenotype-centric variant prioritization in rare genotypes

  4. Andrew Chen

    Machine learning methods for the prediction and exploration of preterm birth

  5. Thomas Coderre

    .html-contained, webassembly-driven: ONE's new environment is a browser app platform for polydnavirus genomics

  6. Callaghan Davitt

    Investigation into the computational modulation and translation of CPG signals to bypass spinal lesions

  7. Sahiba Haji

    Finding evidence for neutral and non-neutral convergent molecular evolution in vertebrate genomes.

  8. Grace Heemeryck

    Development and evaluation of more realistic models of viral evolution

  9. John Hutchinson

    Predicting risk of colorectal cancer using machine learning analysis of genomic sequencing data

  10. Vivian Huynh

    Metabolic flux analysis in glioblastoma using scRNAseq and spatial transcriptome data

  11. Joseph Lam

    Analytical comparison between pharmacogenomic data translation tools for use in research and clinical settings

  12. Kathryn Strayer

    Linking neural activity to motion generation in recurrent neural networks

  13. Abinaya Subramanian

    Support Vector Machine Learning Model Prediction of Gene Signature for Response to Anti-PD-1 Immunotherapy

  14. Alexander Vanc

    Inter and Intra species sequence diversity comparison for surface loops of proteins

  1. Baasil Afzal

    Murine mesenteric lymphatic endothelial cells – isolation and function as potential lymphoid tissue organizers

  2. Aria Ahadzadeh Ardebili

    Fracture toughness following alendronate therapy in ovariohysterectomized rabbits

  3. Monira Alaskar

    Evaluating surface-based analysis of pediatric fMRI data

  4. Modhawi Alqanaie

    Investigating potential therapeutic effects of a direct and selective ERK pathway inhibitor on Fmr1 knockout mice

  5. Munya Alshaalani

    The neuronal activation in the amygdala of Fragile X syndrome in response to social stimuli in vivo

  6. Simran Bains

    In vivo delivery and detection of FMRP fragments in a mouse model of Fragile X Syndrome

  7. Elise Beaupre

    FCGBP fortifies MUC2 mucin in colonic innate defense against Salmonella typhimurium

  8. Stephanie Besoiu

    Construction of alphavirus vectors expressing SARS-CoV-2 structural proteins

  9. Caitlin Calder-Bellamy

    Pro-inflammatory effects of acetylcholine in the airway

  10. Chantelle Carbonell

    Examining the expression of endocannabinoid metabolic enzymes in human gestational tissues

  11. Katie Cooke

    Assessing UCalgary community-academic partnerships for health: a mixed methods

  12. Manimeldura De Silva

    Investigating Moraxella catarrhalis as a secretion system for production of potential vaccine antigens

     

  13. Taylor Deering

    Modulating factors of the metastatic potential of glioblastoma multiforme

  14. Alisha Ebrahim

    A comprehensive analysis of the histological structure and sex-based differences in the novel tubarial glands

  15. Yekta Eslambolchi

    Proteomics investigation of Calpain-3 in limb girdle muscular dystrophy type 2A

  16. Leah Fick

    Administration of vaporized cannabidiol reduces the severity of postictal hypoxia in male rats

  17. Andrew Galbraith

    Computational pipeline for efficient detection of complex genome rearrangments using short-read genome sequencing data

  18. Manvir Gill

    Effect of bisphenol S on vascular function

  19. Tali Glazer

    Characterization of placental histological abnormalities associated with congenital heart defects

  20. Deena Gohar

    The role of electrical activity and trophic factors in the development of hippocampal cholinergic circuits underlying learning and memory

  21. Jing Guo

    Detecting network-level biomarkers of cognitive decline using whole brain connectome and graph theoretical analyses

  22. Liam Hamm

    Investigating the effects of SKA-31 and senicapoc administration on tissue properties in atherosclerosis prone mice

  23. Eve Higgins

    Investigating the role of the WNT signalling pathway in regulating porcine iPS cell self-renewal

  24. Alexis Hill

    Investigating the interactions between biomaterials and mesothelial cells

  25. Hannah Horvath

    Investigating the presence of novel mutations in the isotype-1 β-tubulin gene associated with benzimidazole resistance in the canine hookworm Ancylostoma caninum

  26. Abdul Ilyas

    Impact of lymph flow and neutrophil migration in response to suturing of the efferent lymphatic vessel

  27. Nathalie Irvine

    An examination of the associations between second trimester urinary bisphenol concentrations and changes in gestational and postpartum weight and fat mass in women in the APrON cohort study

  28. Arzina Jaffer

    Molecular mechanisms driving divergent healing outcomes in aged and young mice following skin injury

  29. Kaiden Jobin

    Correlating functional neurological disorder with persistent post concussion syndrome and treatment using transcranial magnetic stimulation.

  30. Faith Keister

    Investigating the relationship between inflammatory biomarkers during pregnancy and short-term outcomes in moderate to late preterm infants 

  31. Akashroop Khaira

    Examining the reliability of quantitative sensory testing

  32. Arshroop Khaira

    The characterization of DNA methylation changes associated with aortopathy in humans

  33. Shahoon Khan

    Investigating the role of mitochondrial fat body metabolism in regulating animal growth and development.

  34. Megan Kinzel

    Investigating the role of mitochondrial fat body metabolism in regulating animal growth and development.

  35. Alexa Krala

    Contribution of novel Gardnerella species to vaginal biofilms and recurrent bacterial vaginosis

  36. Julie Le

    Sodium citrate sensitizes multidrug-resistant Pseudomonas aeruginosa to triclosan

  37. Sophia Lu

    Investigating the role and reglation of miRNA-210-3p in fibroblasts under varying hypoxic conditions

  38. Mehr Malhotra

    Development of a novel intravital imaging analysis platform to evaluate vessel co-option and metastatic potential for cancer research

  39. Sofia Maruschak-Love

    Investigation of variants in the Progesterone Receptor Gene (PGR) in preterm birth

  40. Jackson McLean

    Dynamically examining the angiogenic, metastatic, and tumour growth potential of high-risk human neuroblastoma in the chicken chorioallantoic membrane model

  41. Samantha Miller

    Impact of trauma on resting brain networks and the development of pain symptomology

  42. Armaan Mohan

    Investigating NMIIC in the context of mitochondrial fission

  43. Giulianna Mosca

    Serial thrombelastography and platelet mapping can be used to define hypercoagulability and platelet hyperactivity in pregnancy.

  44. Sathvika Mudigonda

    Elucidating the role of Prx1 in promoting the expression of Prg4  in mesodermal-derived progenitor cells

  45. Kyle Murdy

    Investigating the presence of transferrin and lactoferrin receptors in the upper respiratory tract of mice

  46. Eman Nassef

    Selection of DNA aptamers targeting lymphotoxin-α

  47. Theodore Nelson

    Examining inflammatory alveolar macrophageExamining inflammatory alveolar macrophage phenotypes and barrier function in 2D and 3D co-culture systems phenotypes and barrier function in 

  48. Aisling Ogilvie

    The use of oscillation patterns in determining the effectiveness of various chemotherapy treatments

  49. Matthew O'Neill

    Further characterization of neonatal liver sinusoidal endothelial cells in mice

  50. Kaitlyn Paltzat

    Investigating the Neurological Mechanisms Underlying Cannabis-Driven Feeding Behaviours in a Delta-9-tetrahydracannabinol (THC)-Vaporized Rat Model

  51. Benjamin Perks

    Comparing monocyte fate and activation mediated by chronic Leishmania amazonensis and self-healing Leishmania major infection.

  52. Thea Placsko

    Establishment of an operant oral morphine self-administration model and assessment of the effects of orexin receptor signalling on reinstatement

  53. Sergio Plazas

    In-silico epitope prediction on the glycoprotein E2 of border disease virus. 

  54. Michael Potemkin

    Natural killer cell cytotoxic activity in patients with SARS-CoV-2

  55. Lauren Rusk

    Assessing the effect of synaptic zinc and ketamine on a depressive-like phenotype in a mouse model

  56. Fatima Saleem

    Neutrophil clearance following Staphylococcus aureus skin infection

  57. Lindsey Scott

    Development of an in vivo killing assay to measure T-cell mediated vaccine responses

  58. Alison Sears

    The transcription factor TCF7L2E isoform acts in a specific domain-dependent manner to regulate epithelial-mesenchymal transition: implication in breast cancer

  59. Ashar Siddiqui

    Characterizing the biology of the molecular subtypes of lung squamous cell carcinoma

  60. Shaelene Standing

    Determining the role of Semaphorin 3fa in the ciliary marginal progenitor zone of the eye

  61. Isabelle Tahmazian

    Determining the role of Semaphorin 3fa in the ciliary marginal progenitor zone of the eye

  62. Jacquelyn Tran

    Role of cathelicidin on macrophage phagocytosis during Toxoplasma gondii infection

  63. Kristen Tran

    Proteolysis-derived peptides participate in intestinal epithelial repair.

     

  64. Thuy-Ann Tran

    The role of prolactin receptor in beta cell adaptation to pregnancy

  65. Jessica Wager

    ROS activation of the SAPK pathway in BPS-induced adipogenesis

  66. Sara Zulyniak

    White matter connectivity in youth with treatment resistant depression

  1. Adibba Adel

    Longing to belong: a cross-sectional survey of medical student sense of belonging across Canada

  2. Isabella Alatorre

    Regional Variation of Caesarean Sections in the Dominican Republic

  3. Justin Travis Ancheta

    Supporting older adults with hearing and/or vision impairments at peter coyle place

  4. Sarina Aryal

    Child bicyclist perceptions' of injury risk and safety: the role of the built environment 

  5. Jasleen Brar

    Vulnerabilities and capacities of temporary foreign workers (TFW) employed in essential health care during the COVID-19 pandemic

  6. Lauren Conn

    Symbolic interactionist understandings of the internet: a qualitative study of Canadian undergraduate students aged 18-24. 

  7. Jennifer Fry

    Enhancing access to addiction and mental health services using Centralized Intake in rural Alberta during COVID-19

  8. Slane Hahn

    Queer Eye on Medicine: An investigation of the lived experiences of transgender medical students in Canada

  9. Jennis Jiang

    effectiveness and implementation considerations for audit & feedback in rehabilitation: an environmental scan 

     

  10. Kate McLennan

    Victims, villains, and cheats: A thematic analysis of disability in news media during the COVID-19 pandemic in Alberta.

  11. Donovan Seidel

    Referrals to a mental health service for persons with intellectural disabilities: Caregiver concerns and behavioural ratings

     

  12. Muning Zhang

    Exploring the commonalities and impacts of James Lind Alliance Priority Setting Partnerships in child and youth health

Fatima

MDSC 508 has been instrumental to my BHSc experience. It’s the amalgamation of all the techniques we learned throughout the degree, including project design, execution, and dissemination. The course equips students with both the practical and soft skills needed to succeed in all realms of research. Basically, it's been 'pHun'!

Fatima Iqbal

Class of 2021