508

Honours Thesis

508

Congrats!

Honours thesis students, research supervisors, co-supervisors and preceptors involved in the MDSC 508 capstone course celebrate at the end of the successful oral defenses of the honours theses.  This celebration recognizes the hard work and investment of our students in their thesis research projects and marks the culmination of their undergraduate program. What an accomplishment!

MDSC 508 Honours Thesis Project Titles 2023-2024

The MDSC 508 course is a research-intensive, full-year course taken in the final year of study. The objective is for the student to demonstrate the capacity to conduct a piece of original work in a specific field. 

  1. Abdullah Zubair

    Development and evaluation of a machine learning-based image classification web application for mosquito species identification for species present in Alberta, Canada

  2. Anandita Mahika

    Quantitative characterization of heterozygous NOSIP embryos

  3. Courtney Lenz

    Evaluating the impact of quality control filters and imputation reference panels on pharmacogenomic variant calling

  4. Farbod Moghaddam

    Developing a computer vision algorithm to distinguish between different antinuclear antibody patterns

  5. Fares Senjar

    Analyzing the role of TGF-β signaling in driving phenotypic variation during craniofacial development in zebrafish

  6. Keerthana Chockalingam

    Single-cell transcriptomic characterization of human acute burn wounds to identify targets to promote skin regeneration

  7. Kennedy Romick

    A machine learning-based analysis of sleep as a risk factor for cardiovascular disease

  8. Matthew Yacoub

    A neuro-chip application approach to define electrical activity patterns of identified neurons underlying neuronal growth and synaptic connectivity

  9. Nemanja Grujic

    Development of a senescence-specific promote for accurate cellular senescence detection and mechanistic insights

  10. Noelle Thundathil

    Developing a nanopore amplicon sequencing pipeline for the detection of anthelmintic drug resistance SNPs in gastrointestinal nematodes

  11. Ramin Kahidi

    Enabling personalized mental imagery action detection for children with cerebral palsy

  12. River Sanoy

    Analyzing neurodevelopment and its variability by linking neuroimaging and genetic data

  13. Saahim Salman

    Predicting progression in secondary progressive multiple sclerosis using deep learning models

  14. Sam Lokanc

    Generation of immune stimulating peptides (ISPs) for refractory and recurrent pediatric cancers

  15. Sergiu Cociuba

    Using computer vision to predict optimal vitamin D dosage

  16. Stephen Moore

    Generalizability of deep learning-based magnetic resonance imaging reconstruction models

  1. Aarti Iyer

    The difference in the activity and local connectivity between the seizure onset zone and other areas in the brain as detected by fMRI

  2. Abeer Ahmed

    Determining the impact of oxygen levels on astrocyte immune functions and metabolism

  3. Akila Kularatne

    Determining the distribution and prevalence of transferrin receptor expressing bacteria in mammals

  4. Alessia DiMarzo

    Investigating the prostaglandin E2 pathway and single nucleotide polymorphisms of prostaglandin E2 receptor subtype 3 (PTGER3) and preterm birth

  5. Anita Szabo

    Brain responses to placebo analgesia and nocebo hyperalgesia in youth

  6. Anup Jay

    Investigating the potential of a peptide replacement strategy for Fragile X Syndrome to correct abnormal brain activity in a female Fmr1 KO mouse model

  7. Ashley Clark

    Identification of solute carrier transporters in human gestational tissues and the effects of labour on the gene expression

  8. Aydin Herik

    The spatial and temporal role of protease dysregulation in Citrobacter rodentium colitis

  9. Barak Bader

    Reversal of endothelial dysfunction: Investigating KCa channel activation as a potential beneficial strategy in an estrogen-deficient mouse model

  10. Bilal Shakir

    The role of Fgf8 in patterning face shape variation

  11. Brian Choi

    Interleukin-4 and the regulation of macrophage mitochondrial dynamics

  12. Cassie Wood

    DNGR-1-signaling drives the recruitment of a dedicated cross-presentation enhancing apolipoprotein, APOL7C

     

  13. Connor McCafferty

    A comparative analysis of tissue clearing protocols for the deep tissue imaging and 3D reconstruction of cardiac vasculature

  14. Deborah Ola

    Differential neutrophil responses to healing and non-healing Leishmania  species: Implications for disease manifestations and control

  15. Derek Cheung

    Investigation of AAV-MEDI4893* for staphylococcal alpha-toxin challenge in a mice model

  16. Dewuni De Silva

    Improving precision genome editing through enhanced production and delivery of virus-like particles

  17. Elaha Niazi

    Body composition changes among females treated with in-vitro fertilization: A pilot study

  18. Elliot Peace

    Utilizing a transgenic Collagen 1-eGFP mouse line to study the involvement of fibrocytes in the development of intestinal fibrosis

  19. Fatemah AlAwadhi

    The effects of chemotherapeutics on skin- vs nerve-derived Schwann cells

  20. Ghadir Alhindal

    Mapping the factor associated with neutral sphingomyelinase activation (FAN) interactome and potential effectors of secretory autophagy

  21. Isaac Obrigewitsch

    Investigating the origin of muscle weakness in children with cerebral palsy

  22. Jackie Tran

    Evaluating the role of ER-stress and major ER chaperone, BiP, in promoting survival of human embryonic stem cells following dissociation with TTNPB treatment

  23. Jenna Salem

    An investigation into the association of hyperandrogenism and cardiometabolic disease in females with polycystic ovary syndrome

  24. Jillian Kitt

    In sickness and in fear: investigating the perception and neurobehavioural responses of Lymnaea stagnalis to varying stressors

  25. Jonathan Brill

    Investigating the role of macrophages in regulating animal growth and development in response to hypoxia

  26. Jonathon Truong

    Time- and dose-dependent effects of mitochondrial reactive oxygen species on adipogenesis in C57BL/6 primary adipocytes

  27. Justin Ma-Phan

    AstroFlies: Developing an animal model to investigate the effects of microgravity on spatial orientation skills

  28. Katrina Melan

    Estrogen as a mediator of sex differences in the development of non-alcoholic fatty liver disease and obesity-associated cardiometabolic disease

  29. Kristen Eiriksson

    Click-linking for enhancing crosslinking mass spectrometry performance and improved interactome mapping

  30. Landon Scholly

    Elucidating the impact of hyaluronan synthase 1-3 expression by inflammatory astrocytes

  31. Laura Fine

    Excision frequencies of Staphylococcal Cassette Chromosome mec (SCCmec) in variant SCCmec type and subtype methicillin-resistant Staphylococcus aureus strains

  32. Mackenzie McManus

    Spatial colonic goblet cell innate host defence towards murine Citrobacter rodentium infection

  33. Madeline Miller

    Prenatal cannabis exposure and infant milestone attainment

  34. Mara Marincas

    Edelfosine promotes LDL uptake in synthetic vascular smooth muscles initiating foam cell formation

  35. Marian Grell

    The regulation and function of HIF-1a signaling in acute pneumococcal pneumonia

  36. Marissa Gordon

    Optimizing treatment for Dravet Syndrome (DS): performing anti-seizure drug screening on brain organoids and characterization of excitatory and inhibitory neuron populations

  37. Maya Reed

    Investigating the comparative efficacy and cardiopulmonary impact of dexmedetomidine, hydromorphone, and ketamine sedation protocols in bearded dragons (Pogona vitticeps).

  38. Monica Bautista

    Investigating the roles of candidate distal and proximal enhancers on regulating the oscillatory HES7 expression in a human segmentation clock model

  39. Muskaan Sharma

    The hyperoxic modulation of spinal oxygen sensor activity

  40. Neil Rajpurohit

    Investigating temozolomide treatment resistance in glioblastoma

  41. Nicholas Cao

    The impact of the intestinal microbiome on the formation of trained immunity

  42. Nidhi Kotikalapudi

    Impact of previous life stressor in the response to repetitive transcranial magnetic stimulation (rTMS) treatment in patients with post-concussion symptoms

  43. Ria Mangat

    Repeatability analysis of bone mineral density measurements in weight bearing, cone beam computed tomography

  44. Riley Fedoruk

    Analyzing the role of vesicular zinc neurotransmission in the action of the atypical psychedelic compound ketamine

  45. Riley Gill

    Examining the effect of SB-334867 orexin antagonist in reducing fentanyl relapse behaviours - A self administration model

  46. Ronan Lopes

    Elucidating the activity of β-adrenergic receptors in orthotopic xenograft mouse glioblastoma models

  47. Ryan Bui

    Examining the effects of the patient mutation M978V on USP15 subcellular localization and neuronal migration in the cerebral cortex

  48. Sahara Mand

    Assessing the impact of placental trophoblast gene function on embryonic brain development

  49. Samyah Alsuwaileh

    Role of MEN1 gene and menin protein in Alzheimer's disease

  50. Shrijeet Yennawar

    Characterizing "the munchies"; the effects of tetrahydrocannabinol (THC) vapour inhalation on the activity of appetite-regulating brain regions in a rat model

  51. Shuvam Prasai

    Region-specific activity of phosphodiesterase 9A in angiotensin II-mediated hypertensive heart disease and its influence on cardiac function

  52. Taye Louie

    Optical tweezers and vibrational analysis - a novel approach for cell phenotyping

  53. Treeva Hakim

    Investigating the relationship between maternal and infant inflammatory biomarker profile around delivery

  54. Valerie Ho

    Understanding the mechanism of ALKAL2/ALK signaling in pain-sensing neurons

  55. Yuki Ferguson

    Expression of phosphodiesterase isoforms in rat mesenteric lymphatic endothelial cells and lymphatic muscle cells

  1. Alexia Lee

    Impact of a mandatory nonmedical switch policy from biologics to biosimilars in rheumatoid arthritis patients in Alberta: a longitudinal cohort study

  2. Amelia Wells

    Exploring innovations and factors that optimize adult inpatient flow for neurosurgical care in Alberta: An environmental scan

  3. Amrit Thandi

    Sociodemographic variability of metformin utilization via retail pharmacies across Canada from 2021-2023

  4. Anabel Selemon

    Understanding arbovirus researcher and decision maker user experience in developing an arbovirus serosurveillance health informatics platform

  5. Batool AlMousawi

    Towards equitable employment: Academic researchers' perspectives on establishing a social enterprise for participatory research

  6. Elizabeth Filip

    The impact of travel time and distance to pediatric cancer centres on survival in Alberta: a CYP-C investigation

  7. Erika Pichette

    Perspectives of midwifery clients on midwives as maternity care providers.

  8. Gulshan Baloch

    Coming soon

  9. Huzaifa Kamal

    Investigating the cultural competency of primary healthcare in Alberta

     

  10. Inara Lalani

    Interdisciplinary approaches to defining and detecting child-appealing unhealthy food advertisements in digital media

  11. Lauren Asaad

    Patient perspectives on "care-full" approaches to publishing patient photographs in online medical journals

     

  12. Lyah Ng

    Associations between parental and child physical activity and sedentary behaviour during the initial months of the COVID-19 outbreak.

  13. Parker Diggle

    Building knowledge together: An inclusive research project

  14. Reeana Tazreean

    Ethics in cardiac surgery recovery guidelines: Patient and healthcare provider perspectives

  15. Sanam Sekandary

    Prenatal cannabis consumption and neonatal health outcomes following the legalization of cannabis in Canada

Completing MDSC 508 was among the most impactful learning experiences of my degree. My peers and I took ownership of our research projects, appraised the theoretical frameworks underpinning our disciplines, and developed the ability to effectively communicate the implications of our work. We emerge from this experience equipped with critical thinking and problem solving skills that will enrich our future work and study.

Inara

Inara Lalani

Class of 2024