Honours Thesis
Congrats!
Honours thesis students, research supervisors, co-supervisors and preceptors involved in the MDSC 508 capstone course celebrate at the end of the successful oral defenses of the honours theses. This celebration recognizes the hard work and investment of our students in their thesis research projects and marks the culmination of their undergraduate program. What an accomplishment!
MDSC 508 Honours Thesis Project Titles 2023-2024
The MDSC 508 course is a research-intensive, full-year course taken in the final year of study. The objective is for the student to demonstrate the capacity to conduct a piece of original work in a specific field.
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Abdullah Zubair
Development and evaluation of a machine learning-based image classification web application for mosquito species identification for species present in Alberta, Canada
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Anandita Mahika
Quantitative characterization of heterozygous NOSIP embryos
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Courtney Lenz
Evaluating the impact of quality control filters and imputation reference panels on pharmacogenomic variant calling
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Farbod Moghaddam
Developing a computer vision algorithm to distinguish between different antinuclear antibody patterns
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Fares Senjar
Analyzing the role of TGF-β signaling in driving phenotypic variation during craniofacial development in zebrafish
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Keerthana Chockalingam
Single-cell transcriptomic characterization of human acute burn wounds to identify targets to promote skin regeneration
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Kennedy Romick
A machine learning-based analysis of sleep as a risk factor for cardiovascular disease
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Matthew Yacoub
A neuro-chip application approach to define electrical activity patterns of identified neurons underlying neuronal growth and synaptic connectivity
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Nemanja Grujic
Development of a senescence-specific promote for accurate cellular senescence detection and mechanistic insights
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Noelle Thundathil
Developing a nanopore amplicon sequencing pipeline for the detection of anthelmintic drug resistance SNPs in gastrointestinal nematodes
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Ramin Kahidi
Enabling personalized mental imagery action detection for children with cerebral palsy
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River Sanoy
Analyzing neurodevelopment and its variability by linking neuroimaging and genetic data
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Saahim Salman
Predicting progression in secondary progressive multiple sclerosis using deep learning models
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Sam Lokanc
Generation of immune stimulating peptides (ISPs) for refractory and recurrent pediatric cancers
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Sergiu Cociuba
Using computer vision to predict optimal vitamin D dosage
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Stephen Moore
Generalizability of deep learning-based magnetic resonance imaging reconstruction models
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Aarti Iyer
The difference in the activity and local connectivity between the seizure onset zone and other areas in the brain as detected by fMRI
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Abeer Ahmed
Determining the impact of oxygen levels on astrocyte immune functions and metabolism
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Akila Kularatne
Determining the distribution and prevalence of transferrin receptor expressing bacteria in mammals
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Alessia DiMarzo
Investigating the prostaglandin E2 pathway and single nucleotide polymorphisms of prostaglandin E2 receptor subtype 3 (PTGER3) and preterm birth
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Anita Szabo
Brain responses to placebo analgesia and nocebo hyperalgesia in youth
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Anup Jay
Investigating the potential of a peptide replacement strategy for Fragile X Syndrome to correct abnormal brain activity in a female Fmr1 KO mouse model
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Ashley Clark
Identification of solute carrier transporters in human gestational tissues and the effects of labour on the gene expression
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Aydin Herik
The spatial and temporal role of protease dysregulation in Citrobacter rodentium colitis
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Barak Bader
Reversal of endothelial dysfunction: Investigating KCa channel activation as a potential beneficial strategy in an estrogen-deficient mouse model
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Bilal Shakir
The role of Fgf8 in patterning face shape variation
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Brian Choi
Interleukin-4 and the regulation of macrophage mitochondrial dynamics
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Cassie Wood
DNGR-1-signaling drives the recruitment of a dedicated cross-presentation enhancing apolipoprotein, APOL7C
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Connor McCafferty
A comparative analysis of tissue clearing protocols for the deep tissue imaging and 3D reconstruction of cardiac vasculature
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Deborah Ola
Differential neutrophil responses to healing and non-healing Leishmania species: Implications for disease manifestations and control
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Derek Cheung
Investigation of AAV-MEDI4893* for staphylococcal alpha-toxin challenge in a mice model
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Dewuni De Silva
Improving precision genome editing through enhanced production and delivery of virus-like particles
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Elaha Niazi
Body composition changes among females treated with in-vitro fertilization: A pilot study
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Elliot Peace
Utilizing a transgenic Collagen 1-eGFP mouse line to study the involvement of fibrocytes in the development of intestinal fibrosis
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Fatemah AlAwadhi
The effects of chemotherapeutics on skin- vs nerve-derived Schwann cells
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Ghadir Alhindal
Mapping the factor associated with neutral sphingomyelinase activation (FAN) interactome and potential effectors of secretory autophagy
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Isaac Obrigewitsch
Investigating the origin of muscle weakness in children with cerebral palsy
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Jackie Tran
Evaluating the role of ER-stress and major ER chaperone, BiP, in promoting survival of human embryonic stem cells following dissociation with TTNPB treatment
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Jenna Salem
An investigation into the association of hyperandrogenism and cardiometabolic disease in females with polycystic ovary syndrome
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Jillian Kitt
In sickness and in fear: investigating the perception and neurobehavioural responses of Lymnaea stagnalis to varying stressors
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Jonathan Brill
Investigating the role of macrophages in regulating animal growth and development in response to hypoxia
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Jonathon Truong
Time- and dose-dependent effects of mitochondrial reactive oxygen species on adipogenesis in C57BL/6 primary adipocytes
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Justin Ma-Phan
AstroFlies: Developing an animal model to investigate the effects of microgravity on spatial orientation skills
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Katrina Melan
Estrogen as a mediator of sex differences in the development of non-alcoholic fatty liver disease and obesity-associated cardiometabolic disease
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Kristen Eiriksson
Click-linking for enhancing crosslinking mass spectrometry performance and improved interactome mapping
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Landon Scholly
Elucidating the impact of hyaluronan synthase 1-3 expression by inflammatory astrocytes
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Laura Fine
Excision frequencies of Staphylococcal Cassette Chromosome mec (SCCmec) in variant SCCmec type and subtype methicillin-resistant Staphylococcus aureus strains
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Mackenzie McManus
Spatial colonic goblet cell innate host defence towards murine Citrobacter rodentium infection
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Madeline Miller
Prenatal cannabis exposure and infant milestone attainment
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Mara Marincas
Edelfosine promotes LDL uptake in synthetic vascular smooth muscles initiating foam cell formation
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Marian Grell
The regulation and function of HIF-1a signaling in acute pneumococcal pneumonia
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Marissa Gordon
Optimizing treatment for Dravet Syndrome (DS): performing anti-seizure drug screening on brain organoids and characterization of excitatory and inhibitory neuron populations
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Maya Reed
Investigating the comparative efficacy and cardiopulmonary impact of dexmedetomidine, hydromorphone, and ketamine sedation protocols in bearded dragons (Pogona vitticeps).
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Monica Bautista
Investigating the roles of candidate distal and proximal enhancers on regulating the oscillatory HES7 expression in a human segmentation clock model
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Muskaan Sharma
The hyperoxic modulation of spinal oxygen sensor activity
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Neil Rajpurohit
Investigating temozolomide treatment resistance in glioblastoma
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Nicholas Cao
The impact of the intestinal microbiome on the formation of trained immunity
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Nidhi Kotikalapudi
Impact of previous life stressor in the response to repetitive transcranial magnetic stimulation (rTMS) treatment in patients with post-concussion symptoms
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Ria Mangat
Repeatability analysis of bone mineral density measurements in weight bearing, cone beam computed tomography
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Riley Fedoruk
Analyzing the role of vesicular zinc neurotransmission in the action of the atypical psychedelic compound ketamine
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Riley Gill
Examining the effect of SB-334867 orexin antagonist in reducing fentanyl relapse behaviours - A self administration model
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Ronan Lopes
Elucidating the activity of β-adrenergic receptors in orthotopic xenograft mouse glioblastoma models
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Ryan Bui
Examining the effects of the patient mutation M978V on USP15 subcellular localization and neuronal migration in the cerebral cortex
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Sahara Mand
Assessing the impact of placental trophoblast gene function on embryonic brain development
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Samyah Alsuwaileh
Role of MEN1 gene and menin protein in Alzheimer's disease
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Shrijeet Yennawar
Characterizing "the munchies"; the effects of tetrahydrocannabinol (THC) vapour inhalation on the activity of appetite-regulating brain regions in a rat model
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Shuvam Prasai
Region-specific activity of phosphodiesterase 9A in angiotensin II-mediated hypertensive heart disease and its influence on cardiac function
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Taye Louie
Optical tweezers and vibrational analysis - a novel approach for cell phenotyping
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Treeva Hakim
Investigating the relationship between maternal and infant inflammatory biomarker profile around delivery
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Valerie Ho
Understanding the mechanism of ALKAL2/ALK signaling in pain-sensing neurons
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Yuki Ferguson
Expression of phosphodiesterase isoforms in rat mesenteric lymphatic endothelial cells and lymphatic muscle cells
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Alexia Lee
Impact of a mandatory nonmedical switch policy from biologics to biosimilars in rheumatoid arthritis patients in Alberta: a longitudinal cohort study
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Amelia Wells
Exploring innovations and factors that optimize adult inpatient flow for neurosurgical care in Alberta: An environmental scan
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Amrit Thandi
Sociodemographic variability of metformin utilization via retail pharmacies across Canada from 2021-2023
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Anabel Selemon
Understanding arbovirus researcher and decision maker user experience in developing an arbovirus serosurveillance health informatics platform
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Batool AlMousawi
Towards equitable employment: Academic researchers' perspectives on establishing a social enterprise for participatory research
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Elizabeth Filip
The impact of travel time and distance to pediatric cancer centres on survival in Alberta: a CYP-C investigation
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Erika Pichette
Perspectives of midwifery clients on midwives as maternity care providers.
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Gulshan Baloch
Coming soon
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Huzaifa Kamal
Investigating the cultural competency of primary healthcare in Alberta
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Inara Lalani
Interdisciplinary approaches to defining and detecting child-appealing unhealthy food advertisements in digital media
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Lauren Asaad
Patient perspectives on "care-full" approaches to publishing patient photographs in online medical journals
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Lyah Ng
Associations between parental and child physical activity and sedentary behaviour during the initial months of the COVID-19 outbreak.
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Parker Diggle
Building knowledge together: An inclusive research project
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Reeana Tazreean
Ethics in cardiac surgery recovery guidelines: Patient and healthcare provider perspectives
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Sanam Sekandary
Prenatal cannabis consumption and neonatal health outcomes following the legalization of cannabis in Canada
Completing MDSC 508 was among the most impactful learning experiences of my degree. My peers and I took ownership of our research projects, appraised the theoretical frameworks underpinning our disciplines, and developed the ability to effectively communicate the implications of our work. We emerge from this experience equipped with critical thinking and problem solving skills that will enrich our future work and study.
Inara Lalani
Class of 2024