Grants and Publications

Grants received by members of our program and notable publications.

Grants

Grant

Study

Year received

Hereditary/Transthyretin Amyloidosis Canada Research Grant

Clinical, Sonographic and Electrophysiologic Characteristics of Carpal Tunnel Syndrome in Hereditary and Wild-type Transthyretin Amyloidosis.

2021

University of Calgary Cumming School of Medicine Clinical Research Fund Seed Grant Competition

The prevalence, severity and prognostic utility of frailty assessment in transthyretin amyloidosis cardiomyopathy (the FRAILTY-ATTR Study).

2021

Pfizer Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Research in Canada Grant

Canadian Cardiac Amyloidosis PyrophosphatE Imaging Registry (CAPER).

2021

Quality Improvement Grant to Support the Development of Cardiac Amyloid Centers-Pfizer Global Medical Grant

A Province-Wide Transthyretin Amyloidosis Cardiomyopathy Care Pathway to Enhance Quality Care Assessment and Delivery in Alberta.

2021

Canadian Cardiovascular Society/Pfizer Canada Research Fellowship Grant

Identifying and Predicting Response to Tafamidis Therapy in Transthyretin Cardiac Amyloidosis Using Cardiac Magnetic Resonance Imaging.

2021

Canadian Institutes of Health Research Master’s Award Canada Graduate Scholarship

Determinants and Monitoring of Response to disease-modifying therapy for Transthyretin Amyloidosis Cardiomyopathy: The ATTR-CM Study.

2021

Junior Investigator Global ATTR Amyloidosis Research Award

ASPIRE - Defining the Role of Extra-cellular Matrix in Transthyretin Fibrillogenesis and Tissue Tropism.

2021


Publications

PublicationYear published
Robert J.H. Miller, Aakash Shanbhag, Anna M. Michalowska, Paul Kavanagh, Joanna X. Liang, Valerie Builoff, Nowell M. Fine, Damini Dey, Daniel S. Berman and Piotr J. Slomka. Deep Learning–Enabled Quantification of 99mTc-Pyrophosphate SPECT/CT for Cardiac Amyloidosis. Journal of Nuclear Medicine July 20242024
Karan Shahi, Robert JH. Miller, Steven Dykstra, Yuanchao Feng, Jonathan G. Howlett, Victor Jimenez-Zepeda, Jan Veenhuyzen, James A. White, Nowell M. Fine. Factors Influencing Clinical Initiation of Tafamidis Therapy for Transthyretin Amyloidosis Cardiomyopathy: A Canadian Referral Center Experience. Accepted for publication in the Canadian Journal of Cardiology August 2024.2024
A.Russel, S Khayambashi, N Fine, S Chhibber, C Hahn. Characteristics of Carpal Tunnel Syndrome in Wild-Type Transthyretin Amyloidosis. Can J Neurol Sci. Accepted July 2023.2023
T Perera, S Khayambashi, G Jewett, C Hahn, S McCulloh, J Joseph, S Chhibber. Plasmapheresis for Treatment of Light Chain Amyloidosis Related Myopathy. Can J Neurol Sci. Accepted March 2023.2023
 K Elzinga, S Khayambashi, C Hahn, E Mahe, N Fine. Amyloidosis and Carpal Tunnel Syndrome: Surgical Technique for Extended Carpal Tunnel Release with Tenosynovium and Transverse Carpal Ligament Biopsies. Plastic and Reconstructive Surgery Global Open. Published online January 2023.2023
Slomka PJ, Miller RJH. Can Deep Learning Detect Incidental Abnormal Cardiac Uptake related to Amyloidosis on Routine Bone Scintigraphy? JACC Cardiovasc Imaging 2023. In press.2023
Lee A, Fine N, Bril V, Delago D, Hahn C. Hereditary transthyretin amyloidosis: a case report. Journal of Medical Case Reports. Published online June 24, 2022.2022
Ellen Lewis, Holly Lee, Nowell M. Fine, Robert Miller, Christopher Hahn, Jason Tay, Sameer Chhibber, Etienne Mahe, Victor H.Jimenez-Zepeda. Monoclonal Gammopathy of Undetermined Significance in Patients With Transthyretin Amyloidosis (ATTR): Analysis Using the iStopMM Criteria. Accepted for publication in Clinical Lymphoma, Myeloma and Leukemia December 2022.2022
Kate Elzinga, Shahin Khayambashi, Christopher Hahn, Etienne Mahe, Nowell M. Fine. Amyloidosis and Carpal Tunnel Syndrome: Surgical Technique for Extended Carpal Tunnel Release with Tenosynovium and Transverse Carpal Ligament Biopsies. Accepted for publication in Plastic and Reconstructive Surgery -Global Open November 2022.

2022

 

Roshankar G, White G, Cadet S, Fine N, Chan D, White JA, Jimenez-Zepeda V, Slomka PJ and Miller RJH. Quantitative Cardiovascular Magnetic Resonance and Technetium Pyrophosphate Imaging in Patients with Suspected Cardiac Amyloidosis. J Nucl Cardiol 2022 Oct;29(5):2679-2690.2022

Ellen Lewis, Nowell M. Fine, Robert J. H. Miller, Christopher Hahn, Sameer Chhibber, Etienne Mahe, Jason Tay, Peter Duggan, Sylvia McCulloch, Nizar Bahlis, Paola Neri, Victor H. Jimenez‑Zepeda. Amyloidosis and COVID‑19: Experience From an Amyloid Program in Canada. Accepted for publication in the Annals of Hematology August 2022.

 

2022
Shahin Khayambashi, Kate Elzinga, Christopher Hahn, Sameer Chhibber, Etienne Mahe, Robert J.H. Miller, James A. White, Jonathan G. Howlett, Victor Jimenez-Zepeda, Nowell M. Fine. Amyloidosis Tissue Confirmation for Tafamidis Eligibility Using Transverse Carpal Ligament and Tenosynovium Biopsy. Accepted for publication in Can J Cardiol June 2022.2022
Nowell M. Fine, Robert Miller. Heart Transplantation for Cardiac Amyloidosis: The Need for High Quality Data to Improve Patient Selection. Accepted for publication in Can J Cardiol May 2022.2022
Angela Lee, Nowell M. Fine, Vera Bril, Diego Delgado, Christopher Hahn. Hereditary Transthyretin Amyloidosis: Case Report of an Unusual Cause presenting with Diarrhea, Anemia, and Peripheral Neuropathy. Accepted for publication in the Journal of Medical Case Reports, May 2022.2022
Biobelemoye Irabor, Jacqueline M Mcmillan, Nowell M. Fine. Assessment and Management of Older Patients with Transthyretin Amyloidosis Cardiomyopathy: Geriatric Cardiology, Frailty Assessment and Beyond. Accepted for publication in Frontiers in Cardiovascular Medicine March 2022.2022
Sperry B, Liu C, Akin E, Bateman T, Bravo P, Chen W, Dilsizian V, Hyafil F, Khor Y, Miller E, Miller RJH, Slart R, Slomka P, and Verberne H. Hot Spot Imaging in Cardiovascular Disease: Joint Position Paper of the SNMMI, ASNC, and EANM. J Nucl Med 2022, in press.2022
Robert JH Miller, Nowell M. Fine. Quantifying is Believing: Techniques for Evaluating Transthyretin Cardiac Amyloidosis Burden For Expanded Clinical Applications. Accepted for publication in the Journal of Nuclear Cardiology, November 2021.2022
Golnaz Roshankar, Geneva C White, Sebastien Cadet, Nowell M. Fine, Denise Chan, James A White, Victor Jimenez-Zepeda, Piotr J Slomka, Robert JH Miller. Quantitative Technetium Pyrophosphate and Cardiovascular Magnetic Resonance in Patients with Suspected Cardiac Amyloidosis. Accepted for publication in the Journal of Nuclear Cardiology August 2021.2021
Nowell M. Fine, Jacqueline M. McMillan. Prevalence and Prognostic Significance of Frailty Among Patients with Transthyretin Amyloidosis Cardiomyopathy. Accepted for publication in Circulation Heart Failure March 2021.2021
Victor H. Jimenez-Zepeda, Holly Lee, Nowell M. Fine, Sylvia McCulloch, Jason Tay, Peter Duggan, Paola Meri, Nizar Bahlis. Cyclophosphamide, Bortezomib and Methylprednisolone (CyBorMe) for the Treatment of AL Amyloidosis: Initial Experience from a Single Center. Accepted by the Indian Journal of Hematology and Blood Transfusion January 2021.2021
Miller RJH, Cadet S, Mah D, Pournazari P, Chan D, Fine N, Berman DS, Slomka PJ. Diagnostic and Prognostic Value of Technetium-99m Pyrophosphate Uptake Quantitation for Transthyretin Cardiac Amyloidosis. J Nucl Cardiol 2021, 28:1835–1845.2021
Miller RJH and Fine NM. Quantifying is Believing: Techniques for Evaluating Transthyretin Cardiac Amyloidosis Burden For Expanded Clinical Applications. J Nucl Cardiol. 2021, in press2021
Angela Russell, Christopher Hahn, Sameer Chhibber, Lawrence Korngut, Nowell M. Fine. Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients. Accepted for publication in the Canadian Journal Neurosciences December 2020.2020
Nowell M. Fine. Disease-Modifying Therapy for Transthyretin Amyloidosis: Where to Start? Where to Stop? Accepted for publication in JACC: Case Reports. November 2020.2020
Nowell M. Fine, James A. White, Victor Jimenez Zepeda, Jonathan G. Howlett. Determinants and Prognostic Significance of Serial Right Heart Function Assessment in Patients with Cardiac Amyloidosis. Canadian Journal of Cardiology 2020;36(3):432-440.2020
Nowell M. Fine. Challenges and Strategies in the Diagnosis of Cardiac Amyloidosis. Canadian Journal of Cardiology 2020;36(3):441-3.2020
Erin Karlstedt, Victor Jimenez-Zepeda, Jonathan G. Howlett, James A. White, Nowell M. Fine. Clinical Experience Using Doxycycline and Ursodeoxycholic Acid for the Treatment of Transthyretin Cardiac Amyloidosis. Accepted for publication in the Journal of Cardiac Failure January 2019;25(3):147-53.2019
Na’ama Avitzur, Alessandro Satriano, Mohammad Afzal, Mariam Narous, Yoko Mikami, Reis Hansen, Gary Dobko, Jacqueline Flewitt, Carmen P. Lydell, Andrew G. Howarth, Nowell M. Fine, James A. White. 3D Myocardial Deformation from Cine MRI as a Marker of Amyloid Protein Burden in Cardiac Amyloidosis: Validation versus T1 mapping based measures. International Journal Cardiovascular Imaging. Dec 2018;34(12):1937-19462018
James A. White, Nowell M. Fine. Recent Advances in Cardiovascular Imaging Relevant to the Management of Patients with Suspected Cardiac Amyloidosis. Current Cardiology Reports. August 2016;18(8):77.2016