Next Generation Sequencing
Download our Quick Guide to Getting Started with CHGI - NGS.
Centre for Health Genomics and Informatics
From transcriptome to whole-genome sequencing, CHGI delivers exceptional data quality, industry-leading throughput, and cost-efficient sequencing at scale.
The Centre for Health Genomics and Informatics (CHGI) is a full service core infrastructure facility offering next generation sequencing (NGS) services and bioinformatics support to researchers across the University of Calgary and other research institutions.
Researchers need only submit isolated genomic DNA or total RNA and we will perform all the following steps, from NGS library preparation through to generation of lists of variants or expressed genes. A wide variety of NGS applications are supported.
We aim to build the technological, bioinformatics and human resource capacities required to support the research and health care needs of our university and province, in alignment with Precision Medicine and Precision Health strategies.
Consulting and Project Planning
Please arrange a meeting to discuss sample requirements, replicates, and sequencing options before beginning new NGS projects.
Analytical Services
Services are available for assessing DNA and RNA samples or user-prepared NGS libraries.
Library Preparation Services
We offer sample prep services for genomic, metagenomic, transcriptomic, and small RNA sequencing as well as targeted sequencing via amplicons or hybridization-capture methods.
Instrumentation
CHGI uses industry-standard sequencing and analytical platforms in a dedicated sequencing laboratory to deliver high-quality data.
Bioinformatics and IT
Resources for data analysis and storage
High-Performance Computing
Compute resources in our private server room and other locations.
Data Storage
Multi-petabyte data storage on disk and tape.
Illumina DRAGEN secondary analysis
Accurate, comprehensive, and efficient secondary analysis of next generation sequencing data.
Bioinformaticians
Bioinformatics staff who can provide additional fee-for-service assistance.
Find information on data storage and bioinformatics services here.