Carol Huang

Associate Professor

Departments of Endocrinology, Medical Science, Pediatrics

Associate Professor

Department of Biochemistry & Molecular Biology

MD, Ph.D (Doctor of Philosophy)



Research and teaching

Research Activities

Our lab is interested in understanding the molecular mechanisms that regulate beta cell mass and function, using pregnancy as the model. We have found that intact prolactin receptor signaling is required for normal glucose homeostasis and beta cell mass expansion during pregnancy. We will now examine 1) whether beta-cell neogenesis occurs during pregnancy, 2) what are the signalling pathways required for the increase in beta-cell mass during pregnancy, and 3) whether pregnancy hormones can improve glucose homeostasis in animal models of type 1 and type 2 diabetes, or the outcomes of islet transplantation. Another area of research is to delineate whether adipokines, hormones secreted by adipocyte, which affect whole body insulin sensitivity, also regulates pancreatic beta-cell mass and function. We also has clinical collaborations examining the relationship between adipokine, obesity, and risk of cardiovascular diseases in children with diabetes.

Dr. Huang is interested in recruiting a PhD graduate student. Please contact Dr. Huang directly if you would like to be considered. 

Research Personnel:

  • Marle Pretorius, Graduate Student
  • Zhao Xiao, Lab manager
  • Shalyn Prasad, Administrative Assistant

Publications

PubMed