Honours Thesis
Congrats!
Honours thesis students, research supervisors, co-supervisors and preceptors involved in the MDSC 508 capstone course celebrate at the end of the successful oral defenses of the honours theses. This celebration recognizes the hard work and investment of our students in their thesis research projects and marks the culmination of their undergraduate program. What an accomplishment!
MDSC 508 Honours Thesis Project Titles 2025-2026
The MDSC 508 course is a research-intensive, full-year course taken in the final year of study. The objective is for the student to demonstrate the capacity to conduct a piece of original work in a specific field.
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Bentley Chai
Development of an Interactive Web Platform for the Visualization of Renal Cancer Patient Clinical, Genomic, Immunopeptidomic Data
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Jui Das
Quantifying representativeness of head and neck squamous cell carcinoma cell lines to patient tumor samples to enhance drug-response biomarker discovery
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Emily Garcia-Volk
Quantification of Craniofacial Cellular Dynamics Using a Nosip Mutant Mouse Model
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Grace Johnson
An informatics approach to understanding the consequences of Canadian residential radon gas exposure: from population effects to cellular genomic stability
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Aidan Moore
Mapping Behavioral Variations to Image Data via a shared Latent Space: A Variational Autoencoder Proof of Concept
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Sahar Ramzan
Regulation of Neural Stem Cell Fate by CELF2 Protein
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Sahar Siraj Ahamed
Quantifying Turbulent Kinetic Energy in Bicuspid Aortic Valve
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Gavin Walters
Modelling H2O2 and Dopaminergic Influence on Calcium Influx and Calcium-feedback Mechanisms in Medium Spiny Neurons
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Amaju-Tuoyo Abati
Investigating the epistatic relationship between Fgf8 and Fgf17 in mouse embryonic development
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Maren Abuzukar
Investigating the Effects of Obesity and Exercise Intervention on Muscle Integrity in High and Low Aerobic Capacity Runner Rats
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Nana Kwame Addo
Investigating Pain-Mood Interactions in Parkinson’s disease in a PINK1 Knockout Rat Model with Sex-Stratified Analyses
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Annaliese Boim
The Effects of APOE ε4 Allele and CD2AP Polymorphism on Cognitive Function and White Matter Hyperintensity in a Cohort with Transient Ischemic Attack
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Lauren Care
Investigating Differences Between Tissue Resident and Newly Recruited Large Peritoneal Macrophages Based on Molecular, Environmental, and Functional Characteristics
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Yi Li Chen
Characterizing the role of epicardial adipose tissue derived stem cells in cellular crosstalk within the context of myocardial infarction
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Schein Chingozho
Exploring the effects of Versican loss on Vascular Smooth Muscle Cells and Extracellular Matrix Proteins
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Antonette Ciepliski
An Investigation into the Effects of Cannabis Vaping on Oxytocin Activity During Social Interaction in Mice
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Jasleen Dhaliwal
Investigating the impact of vape flavourants on resident lung cells in a 3D lung-on-a-chip model
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Gayatri Dronamraju
The Role of Rhodotorula Mucilaginosa, a Core Mycobiome Species, in Host Nutrient Absorption
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Zachary Epp
Project iGABASnFR3: Progress Towards a Third Generation Genetically Encoded Fluorescent Sensor for Gamma-Aminobutyric Acid
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Nyathach Gatluak
Investigating Mechanical Regulation of Transgelin Expression in Human Fibroblasts
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Samuel Gerlach
Investigating Cardiac Intercellular Crosstalk and Secretome Dynamics in Myocardial Ischemia
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Izma Ghani
Following Configural Learning: Can a false memory be implanted in Lymnaea stagnalis?
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Aaranyo Ghosh
Neuroinflammation and febrile seizures: Evaluating CCR2 Inhibition in LPS-treated Hippocampal Brain slices
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Alisa Guri
Investigating extracellular matrix density as a regulator of epithelial-to-mesenchymal transition during Crohn's disease fistula formation
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Hunter Hillock
Fit for Purpose: Biomarker Evaluation of Cortisol by Investigating Short Term Within-Person Variability and Matrix Effects
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Stephanie Huynh
Investigating Hypothalamic Development in Prader-Willi Syndrome Using Human Hypothalamic Organoids
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Areesa Imran
Do Vascular Brain Changes Mediate the Link Between Sleep Quality and Behaviour in Dementia-Free Older Adults? A Cross-Sectional COMPASS-ND Analysis
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Jordan Isberg
Effects of Host-Targeted Therapeutic PUR4 on Influenza A Viral Clearance
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Sophie Kazimirski
Assessing DNA Methylation (DNAm) and its Association with Amyotrophic Lateral Sclerosis (ALS) and Spinal Bulbar Muscular Atrophy (SBMA)
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Mackenzie Kilback
Examining the Effect of PER3 SNP rs228669 and RNA Expression Changes on Preterm Birth Risk
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Hannah Kim
Developing a CD33-Targeting Chimeric Antigen Receptor Double-Negative T Cell Therapy Against Acute Myeloid Leukemia
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Hannah Krahn
Investigating the Expression and Regulation of Histamine Receptors during Pregnancy
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Jaden Lei
Investigating the Synergy of a Synthetic Lethality-Based Therapy with an NRF2 Inhibitor for the Treatment of PTEN-Deficient Osteosarcoma
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Ayesha Malik
Quantification of Microbleeds through Automated MRI Analysis to Guide Disease - Modifying Therapies in Alzheimer’s Disease
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Dyllan Mand
Adverse Childhood Experiences, Brain Microstructure and Pain Sensitization in Adolescents
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Shayne McArthur
Temporal Trends in Antiseptic and Mupirocin Resistance among Staphylococci over 30 years in Alberta, Canada
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Riley Ngo
Limited Impact of Immune Reconstitution on Systemic Sclerosis Relapse after Autologous Hematopoietic Cell Transplantation
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Ogechi Okafor
Meningeal Lymphatic Developmental Defects Impact Neuroinflammation and Brain Morphology
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Ifeolu Owojori
Impact of the R1182C Mutation on Cav2.3 R-type Voltage-Gated Calcium Channel Function
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Dhruvil Patel
Relating Structural Neuroimaging Markers to CSF Biomarker Status in PROMPT Registry Patients with Suspected Alzheimer's Disease
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Ishika Patel
Temperature Sensitivity of Coronavirus Nucleocapsid Protein Antagonism of Antiviral Responses
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Priya Raj
The Mitochondrial Dynamics of Mesenchymal Stem Cells During Mycobacterium tuberculosis Infection
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Rajpreet Randhawa
Understanding the Role of Cholesterol in Modulating Prion Protein Metabolism, Misfolding, and Susceptibility to Prion Infection
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Muhammad Raza
Investigating Mitochondrial DNA Mislocalization and Modulation of Mitophagy Pathways in FBXL4 Deficiency
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Delaney Robinson-Wong
Epitope Mapping Targeting of Alpha-Synuclein Aggregates for Degradation Using Ubiquitin Variant Induced Proximity (UbVIP) Constructs
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Camille Rozon
Investigating mTOR in Matched Newly Diagnosed and Recurrent Glioblastoma Cells
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Arshpreet Saini
Investigating Hypoxia-Driven S.aureus Pathogenesis Using A Lung-on-a-Chip Model
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Hannah Mae Santa Rita
Associations Between Perinatal Clinical Factors, MRI Findings, and Neurodevelopmental Outcomes at One Year in Preterm Infants
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Olivia Sharpe
Longitudinal Changes in Plasma Metabolomic Profiles and Subsequent Risk of Breast Cancer
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Aislyn Shaw
Effect of Disinhibition of the Orbitofrontal Cortex on Food Intake and Weight Gain
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Priya Sinha
Comparative Analysis of Hippocampal Gene Expression Following Stroke: Implications for Memory and Cognitive Decline
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Caleb Small
Exploring fibroblast and immune dynamics driving pro-regenerative skin wound healing
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Dylan Steckler
Investigating the Identity, Ontogeny and Function of Bile Duct Macrophages
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Meera Sylvain
Evaluating Interstitial Glucose Parameters Across Menstrual Cycle Phases in Females with Polycystic Ovary Syndrome
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Renee Ta
High Frequency Oscillations as an Electroencephalography Biomarker for Self-limited Epilepsy with Autonomic Seizures
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Michelle Tang
Characterizing the Immune Landscape of Individuals with Chronic Hepatitis B after Hepatitis B Virus Surface Antigen Loss
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Rachel Taylor
Investigating the Effect of Chimeric Antigen Receptor-Macrophage (CAR-M) Intracellular Signaling Domains on Macrophage Cell Function
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Chelsea Taylor
Messages From Worms: Do Hymenolepis diminuta Extracellular Vesicles Modulate Murine Macrophage Mitochondria?
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Joan Umoh
Characterizing alterations in the neuronal connectivity, activity, and cellular viability of hippocampal neurons in vitro following treatment with ketamine
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Sraddha Uppili
Investigating the Role of Proteases in the Host-Immune Response during Swine Dysentery
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Mikaela Virues
Metabolomics of Acute Respiratory Distress Syndrome: An External Validation Study
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Ella Williams
Magnetic resonance imaging-based prediction of drug treatments in Huntington Disease
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Julia Willson
Beyond Passive Protection: Exploring the Role of Breast Milk Immunoglobulin G in Early Life Anti-Rotaviral Immunity
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Brendan Woodward
Investigating Mitochondrial Dynamics and Impairments in the MYH14 R941L Variant Associated with Peripheral Neuropathy
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Elma Anamali
Development of an Evaluation Framework and Tool for Indigenous Knowledge and Capacity Related to Psychedelic-Based Therapeutics
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Rameen Babar
Sociodemographic Patterning of Behavioural Risk Severity Among At-Risk Hospital Patients in Alberta: Cross-Sectional Analysis of the iPiC-Health Data
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Nina Carcamo Arakawa
Validation of the Punjabi and Tagalog Family ICU Delirium Detection Instrument and Development of Video-Based Questionnaires
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Maya Eboigbodin
Measuring What ACEs Miss: Developing a Structural Harm Tool for Families Affected by Parental Substance Use
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Alexis Espanioli
Building Networks of Care: A Community-Based Qualitative Study Exploring Community and Wraparound Supports in Emergency Food Assistance Programs
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Jaden Frizzell
The Association between Housing Status and Ambulatory Care-Sensitive Conditions in the Emergency Department
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Roisin Gangabadrakh
Will Providing Higher Weekly Subsidies Reduce The Need For Parental Shielding Of Children? A Pragmatic Randomized Controll
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Chantelle Gillies
Examining Patterns and Predictors of Interconnected Wellbeing Needs in the Calgary Community Court
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Hannah Goyan
Factors Affecting Meaningful Change: An Investigation of the Reconciliation Leadership Foundations
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Ella Gulayets
Show and Tell: Participatory Approaches to Understanding Trauma-Informed Design and Child Well-Being in Therapeutic Campus-Based Care: A Qualitative Case Study at Parkdale (Cottage E), Wood’s Homes
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Afia Ibnat
Exploring Sociodemographic Factors Associated With Cervical Cancer Screening Among Mothers in Alberta, Canada
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Inam Khalfan
Exploring Lived Experiences of Gluten-related Conditions Among Indigenous Peoples in: A Qualitative Approach
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Sophie Macdonald
Indicators of Social Media Attention for Transgender and Gender Diverse Research Publications
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Meghan McNaughton
Maternal Language, Child Microstructural Brain Development, and Early Learning: A Longitudinal Study from Ages Two to Three
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Julianne Moore
Exploring Inequities in Head and Neck Cancer Outcomes in Alberta: A Retrospective Cohort Study
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Gayathri Nair
Longitudinal Associations Between Perceived Neighborhood Walkability and Physical Activity in Adults
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Muskaan Pamery
Curating Lived Experiences in Virtual Reality: A Participatory Arts-Based Exploration of Immigrant and Refugee’s Students Multimodal Narratives
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Zoe Aisehsa Pena
Understanding Alcohol Use Across the Cancer Journey: Psychosocial and Structural Determinants in Adolescent and Young Adult Survivors
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Grace Szilagyi
The Soundtrack of Care: Exploring Anesthetists’ Embodied and Affective Engagement with the Clinical Sounds
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Kaia Thauberger
Beyond Retention: A Life Course Analysis of Women’s Rural Medical Careers
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Maddison Tory
Maternal Pain Trajectories, Child Brain Microstructure and Socioemotional Outcomes at Three Years
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Keren Vince
Community Engagement for Health Equity: A Comparative Case Stud
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Samantha Vukadinovic
Experiences and Perspectives Arising from Person-Environment Interactions in the Calgary Plus-15: A Qualitative Analysis of Tripadvisor® Reviews
MDSC 508 was the culmination of all our efforts throughout the BHSc program. The course was a tremendously rewarding experience, pushing us to grow not only as students but independent researchers and setting us up to thrive wherever our next steps may take us. The process of developing our projects, conducting research, and defending our theses in such a collaborative and interdisciplinary environment has been nothing short of a pleasure.
Emily Garcia-Volk
Class of 2026