BINF

Honours Thesis

508

Congrats!

Honours thesis students, research supervisors, co-supervisors and preceptors involved in the MDSC 508 capstone course celebrate at the end of the successful oral defenses of the honours theses.  This celebration recognizes the hard work and investment of our students in their thesis research projects and marks the culmination of their undergraduate program. What an accomplishment!

HSOC

MDSC 508 Honours Thesis Project Titles 2025-2026

The MDSC 508 course is a research-intensive, full-year course taken in the final year of study. The objective is for the student to demonstrate the capacity to conduct a piece of original work in a specific field. 

  1. Bentley Chai

    Development of an Interactive Web Platform for the Visualization of Renal Cancer Patient Clinical, Genomic, Immunopeptidomic Data

  2. Jui Das

    Quantifying representativeness of head and neck squamous cell carcinoma cell lines to patient tumor samples to enhance drug-response biomarker discovery

  3. Emily Garcia-Volk

    Quantification of Craniofacial Cellular Dynamics Using a Nosip Mutant Mouse Model

  4. Grace Johnson

    An informatics approach to understanding the consequences of Canadian residential radon gas  exposure: from population effects to cellular genomic stability

  5. Aidan Moore

    Mapping Behavioral Variations to Image Data via a shared Latent Space: A Variational Autoencoder Proof of Concept

  6. Sahar Ramzan

    Regulation of Neural Stem Cell Fate by CELF2 Protein

  7. Sahar Siraj Ahamed

    Quantifying Turbulent Kinetic Energy in Bicuspid Aortic Valve

  8. Gavin Walters

    Modelling H2O2 and Dopaminergic Influence on Calcium Influx and Calcium-feedback Mechanisms in Medium Spiny Neurons

  1. Amaju-Tuoyo Abati

    Investigating the epistatic relationship between Fgf8 and Fgf17 in mouse embryonic development

  2. Maren Abuzukar

    Investigating the Effects of Obesity and Exercise Intervention on Muscle Integrity in High and Low Aerobic Capacity Runner Rats

  3. Nana Kwame Addo

    Investigating Pain-Mood Interactions in Parkinson’s disease in a PINK1 Knockout Rat Model with Sex-Stratified Analyses

  4. Annaliese Boim

    The Effects of APOE ε4 Allele and CD2AP Polymorphism on Cognitive Function and White Matter Hyperintensity in a Cohort with Transient Ischemic Attack

  5. Lauren Care

    Investigating Differences Between Tissue Resident and Newly Recruited Large Peritoneal  Macrophages Based on Molecular, Environmental, and Functional Characteristics

  6. Yi Li Chen

    Characterizing the role of epicardial adipose tissue derived stem cells in cellular crosstalk within the  context of myocardial infarction

  7. Schein Chingozho

    Exploring the effects of Versican loss on Vascular Smooth Muscle Cells and Extracellular  Matrix Proteins

  8. Antonette Ciepliski

    An Investigation into the Effects of Cannabis Vaping on Oxytocin Activity During Social  Interaction in Mice

  9. Jasleen Dhaliwal

    Investigating the impact of vape flavourants on resident lung cells in a 3D lung-on-a-chip model

  10. Gayatri Dronamraju

    The Role of Rhodotorula Mucilaginosa, a Core Mycobiome Species, in Host Nutrient Absorption

  11. Zachary Epp

    Project iGABASnFR3: Progress Towards a Third Generation Genetically Encoded Fluorescent Sensor for Gamma-Aminobutyric Acid

  12. Nyathach Gatluak

    Investigating Mechanical Regulation of Transgelin Expression in Human Fibroblasts

  13. Samuel Gerlach

    Investigating Cardiac Intercellular Crosstalk and Secretome Dynamics in Myocardial  Ischemia 

  14. Izma Ghani

    Following Configural Learning: Can a false memory be implanted in Lymnaea stagnalis?

  15. Aaranyo Ghosh

    Neuroinflammation and febrile seizures: Evaluating CCR2 Inhibition in LPS-treated Hippocampal Brain slices

  16. Alisa Guri

    Investigating extracellular matrix density as a regulator of epithelial-to-mesenchymal transition during Crohn's disease fistula formation

  17. Hunter Hillock

    Fit for Purpose: Biomarker Evaluation of Cortisol by Investigating Short Term Within-Person Variability and Matrix Effects

  18. Stephanie Huynh

    Investigating Hypothalamic Development in Prader-Willi Syndrome Using Human Hypothalamic Organoids

  19. Areesa Imran

    Do Vascular Brain Changes Mediate the Link Between Sleep Quality and Behaviour in  Dementia-Free Older Adults? A Cross-Sectional COMPASS-ND Analysis

  20. Jordan Isberg

    Effects of Host-Targeted Therapeutic PUR4 on Influenza A Viral Clearance 

  21. Sophie Kazimirski

    Assessing DNA Methylation (DNAm) and its Association with Amyotrophic Lateral Sclerosis (ALS) and Spinal Bulbar Muscular Atrophy (SBMA)

  22. Mackenzie Kilback

    Examining the Effect of PER3 SNP rs228669 and RNA Expression Changes on Preterm Birth Risk

  23. Hannah Kim

    Developing a CD33-Targeting Chimeric Antigen Receptor Double-Negative T Cell Therapy Against Acute Myeloid Leukemia

  24. Hannah Krahn

    Investigating the Expression and Regulation of Histamine Receptors during Pregnancy

  25. Jaden Lei

    Investigating the Synergy of a Synthetic Lethality-Based Therapy with an NRF2 Inhibitor for the Treatment of PTEN-Deficient Osteosarcoma

  26. Ayesha Malik

    Quantification of Microbleeds through Automated MRI Analysis to Guide Disease - Modifying Therapies in Alzheimer’s Disease

  27. Dyllan Mand

    Adverse Childhood Experiences, Brain Microstructure and Pain Sensitization in Adolescents

  28. Shayne McArthur

    Temporal Trends in Antiseptic and Mupirocin Resistance among Staphylococci over 30 years in Alberta, Canada 

  29. Riley Ngo

    Limited Impact of Immune Reconstitution on Systemic Sclerosis Relapse after Autologous Hematopoietic Cell Transplantation

  30. Ogechi Okafor

    Meningeal Lymphatic Developmental Defects Impact Neuroinflammation and Brain Morphology

  31. Ifeolu Owojori

    Impact of the R1182C Mutation on Cav2.3 R-type Voltage-Gated Calcium Channel Function

  32. Dhruvil Patel

    Relating Structural Neuroimaging Markers to CSF Biomarker Status in PROMPT Registry Patients with Suspected Alzheimer's Disease

  33. Ishika Patel

    Temperature Sensitivity of Coronavirus Nucleocapsid Protein Antagonism of Antiviral  Responses

  34. Priya Raj

    The Mitochondrial Dynamics of Mesenchymal Stem Cells During Mycobacterium tuberculosis Infection

  35. Rajpreet Randhawa

    Understanding the Role of Cholesterol in Modulating Prion Protein Metabolism, Misfolding, and Susceptibility to Prion Infection

  36. Muhammad Raza

    Investigating Mitochondrial DNA Mislocalization and Modulation of Mitophagy Pathways in FBXL4 Deficiency

  37. Delaney Robinson-Wong

    Epitope Mapping Targeting of Alpha-Synuclein Aggregates for Degradation Using Ubiquitin Variant Induced Proximity (UbVIP) Constructs 

  38. Camille Rozon

    Investigating mTOR in Matched Newly Diagnosed and Recurrent Glioblastoma Cells

  39. Arshpreet Saini

    Investigating Hypoxia-Driven S.aureus Pathogenesis Using A Lung-on-a-Chip Model

  40. Hannah Mae Santa Rita

    Associations Between Perinatal Clinical Factors, MRI Findings, and Neurodevelopmental Outcomes at One Year in Preterm Infants

  41. Olivia Sharpe

    Longitudinal Changes in Plasma Metabolomic Profiles and Subsequent Risk of Breast Cancer

  42. Aislyn Shaw

    Effect of Disinhibition of the Orbitofrontal Cortex on Food Intake and Weight Gain

  43. Priya Sinha

    Comparative Analysis of Hippocampal Gene Expression Following Stroke: Implications for Memory and Cognitive Decline

  44. Caleb Small

    Exploring fibroblast and immune dynamics driving pro-regenerative skin wound healing

  45. Dylan Steckler

    Investigating the Identity, Ontogeny and Function of Bile Duct Macrophages

  46. Meera Sylvain

    Evaluating Interstitial Glucose Parameters Across Menstrual Cycle Phases in Females with  Polycystic Ovary Syndrome

  47. Renee Ta

    High Frequency Oscillations as an Electroencephalography Biomarker for Self-limited Epilepsy with Autonomic Seizures

  48. Michelle Tang

    Characterizing the Immune Landscape of Individuals with Chronic Hepatitis B after Hepatitis B Virus Surface Antigen Loss

  49. Rachel Taylor

    Investigating the Effect of Chimeric Antigen Receptor-Macrophage (CAR-M) Intracellular Signaling Domains on Macrophage Cell Function

  50. Chelsea Taylor

    Messages From Worms: Do Hymenolepis diminuta Extracellular Vesicles Modulate Murine Macrophage Mitochondria?

  51. Joan Umoh

    Characterizing alterations in the neuronal connectivity, activity, and cellular viability of hippocampal neurons in vitro following treatment with ketamine

  52. Sraddha Uppili

    Investigating the Role of Proteases in the Host-Immune Response during Swine Dysentery

  53. Mikaela Virues

    Metabolomics of Acute Respiratory Distress Syndrome: An External Validation Study

  54. Ella Williams

    Magnetic resonance imaging-based prediction of drug treatments in Huntington Disease 

  55. Julia Willson

    Beyond Passive Protection: Exploring the Role of Breast Milk Immunoglobulin G in Early Life Anti-Rotaviral Immunity

  56. Brendan Woodward

    Investigating Mitochondrial Dynamics and Impairments in the MYH14 R941L Variant Associated with Peripheral Neuropathy

  1. Elma Anamali

    Development of an Evaluation Framework and Tool for Indigenous Knowledge and Capacity Related to Psychedelic-Based Therapeutics

  2. Rameen Babar

    Sociodemographic Patterning of Behavioural Risk Severity Among At-Risk Hospital Patients in Alberta: Cross-Sectional Analysis of the iPiC-Health Data

  3. Nina Carcamo Arakawa

    Validation of the Punjabi and Tagalog Family ICU Delirium Detection Instrument and Development of Video-Based Questionnaires

  4. Maya Eboigbodin

    Measuring What ACEs Miss: Developing a Structural Harm Tool for Families Affected by Parental Substance Use

  5. Alexis Espanioli

    Building Networks of Care: A Community-Based Qualitative Study Exploring Community and Wraparound Supports in Emergency Food Assistance Programs

  6. Jaden Frizzell

    The Association between Housing Status and Ambulatory Care-Sensitive Conditions in the  Emergency Department

  7. Roisin Gangabadrakh

    Will Providing Higher Weekly Subsidies Reduce The Need For Parental Shielding Of Children? A  Pragmatic Randomized Controll

  8. Chantelle Gillies

    Examining Patterns and Predictors of Interconnected Wellbeing Needs in the Calgary Community Court

  9. Hannah Goyan

    Factors Affecting Meaningful Change: An Investigation of the Reconciliation Leadership Foundations

  10. Ella Gulayets

    Show and Tell: Participatory Approaches to Understanding Trauma-Informed Design and  Child Well-Being in Therapeutic Campus-Based Care: A Qualitative Case Study at Parkdale (Cottage E), Wood’s Homes

  11. Afia Ibnat

    Exploring Sociodemographic Factors Associated With Cervical Cancer Screening Among Mothers in Alberta, Canada

  12. Inam Khalfan

    Exploring Lived Experiences of Gluten-related Conditions Among Indigenous Peoples in: A Qualitative Approach

  13. Sophie Macdonald

    Indicators of Social Media Attention for Transgender and Gender Diverse Research Publications

  14. Meghan McNaughton

    Maternal Language, Child Microstructural Brain Development, and Early Learning: A  Longitudinal Study from Ages Two to Three

  15. Julianne Moore

    Exploring Inequities in Head and Neck Cancer Outcomes in Alberta: A Retrospective Cohort Study

  16. Gayathri Nair

    Longitudinal Associations Between Perceived Neighborhood Walkability and Physical Activity in Adults 

  17. Muskaan Pamery

    Curating Lived Experiences in Virtual Reality: A Participatory Arts-Based Exploration of Immigrant and Refugee’s Students Multimodal Narratives

  18. Zoe Aisehsa Pena

    Understanding Alcohol Use Across the Cancer Journey: Psychosocial and Structural Determinants in Adolescent and Young Adult Survivors

  19. Grace Szilagyi

    The Soundtrack of Care: Exploring Anesthetists’ Embodied and Affective Engagement with the  Clinical Sounds

  20. Kaia Thauberger

    Beyond Retention: A Life Course Analysis of Women’s Rural Medical Careers

  21. Maddison Tory

    Maternal Pain Trajectories, Child Brain Microstructure and Socioemotional Outcomes at Three Years

  22. Keren Vince

    Community Engagement for Health Equity: A Comparative Case Stud

  23. Samantha Vukadinovic

    Experiences and Perspectives Arising from Person-Environment Interactions in the Calgary Plus-15: A Qualitative Analysis of Tripadvisor® Reviews

Emily

MDSC 508 was the culmination of all our efforts throughout the BHSc program. The course was a tremendously rewarding experience, pushing us to grow not only as students but independent researchers and setting us up to thrive wherever our next steps may take us. The process of developing our projects, conducting research, and defending our theses in such a collaborative and interdisciplinary environment has been nothing short of a pleasure.

Emily

Emily Garcia-Volk

Class of 2026