Research

Research and Publications

Top Papers First Authored by Fellows

Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy.
PA Barber, AM Demchuk, J Zhang, AM Buchan, ASPECTS Study Group
The Lancet 355(9216), 1670-1674
CITATIONS: 1847
YEAR: 2000

Why are stroke patients excluded from TPA therapy?:  An analysis of patient eligibility
PA Barber, J Zhang, AM Demchuk, MD Hill, AM Buchan
Neurology 56 (8), 1015-1020
CITATIONS: 828
YEAR: 2001

Low Rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke:  real-world experience and a call for action.
R Bhatia, MD Hill, N Shobha, B Menon, S Bal, P Kochar, T Watson, M Goyal, AM Demchuk
Stroke 41 (10), 2254-2258
CITATIONS: 650
YEAR: 2010

Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER):  a randomised controlled pilot trial
J Kennedy, MD Hill, KJ Ryckborst, M Eliasziw, AM Demchuk, AM Buchan: Faster Investigators
The Lancet Neurology 6 (11), 961-969
CITATIONS: 617
YEAR: 2007

Defining hematoma expansion in intracerebral hemorrhage:  relationship with patient outcomes
D Dowlatshahi, AM Demchuk, ML Flaherty, M Ali, PL Lyden, EE Smith
Neurology 76 (14), 1238-1244
CITATIONS: 328
YEAR: 2011

Triaging transient ischemic attack and minor stroke patients using acute magnetic resonance imaging
SB Coutts, JE Simon, M Eliasziw, CH Sohn, MD Hill, PA Barber, V Palumbo, J Kennedy, J Roy, A Gagnon, JN Scott, AM Buchan, AM Demchuk
Annals of Neurology 2005 Jun;57(6):848-54
CITATIONS: 299
YEAR: 2005

Extent of early ischemic changes on computed tomography (CT) before thrombolysis:  prognostic value of the Alberta Stroke Program Early CT Score in ECASS II
I Dzialowski, MD Hill, SB Coutts, AM Demchuk, DM Kent, O Wunderlich, R von Kummer
Stroke 37 (4), 973-978
CITATIONS: 269
YEAR: 2006 

Regional leptomeningeal score on CT angiography predicts clinical and imaging outcomes in patients with acute anterior circulation occlusions
BK Menon, EE Smith, J Modi, SK Patel, R Bhatia, TWJ Watson, MD Hill, AM Demchuk, M Goyal
American Journal of Neuroradiology 32 (9), 1640-1645
CITATIONS: 241
YEAR: 2011

Intracranial thrombus extent predicts clinical outcome, final infarct size and hemorrhagic transformation in ischemic stroke:  the clot burden score
V Puetz, I Dzialowski, MD Hill, S Subramaniam, PN Sylaja, A Krol, C O’Reilly, ME Hudon,
WY Hu, SB Coutts, PA Barber, T Watson, J Roy, AM Demchuk, Calgary CTA Study Group
International Journal of Stroke 3 (4), 230-236
CITATIONS: 233
YEAR: 2008

Thrombolysis in patients older than 80 years with acute ischaemic stroke:  Canadian Alteplase for Stroke Effectiveness Study
PN Sylaja, R Cote, AM Buchan, MD Hill
Journal of Neurology, Neurosurgery & Psychiatry 77 (7), 826-829
CITATIONS: 211
YEAR: 2006

Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysis
AY Poppe, SR Majumdar, T Jeerakathil, W Ghali, AM Buchan, MD Hill
Diabetes Care 32(4), 617-622
CITATIONS: 202
YEAR: 2009

Extent of hypoattenuation on CT angiography source images predicts functional outcome in patients with basilar artery occlusion
V. Puetz, PN Sylaja, SB Coutts, MD Hill, I Dzialowski, P Mueller, U Becker, G Urban, C O’Reilly, PA Barber, P Sharma, M Goyal, G Gahn, R von Kummer, AM Demchuk
Stroke 39(9), 2485-2490
CITATIONS: 202
YEAR: 2008

Risk score for intracranial hemorrhage in patients with acute ischemic stroke treated with intravenous tissue-type plasminogen activator
BK Menon, JL Saver, S Prabhakaran, M. Reeves, L Liang, DWM Olson, ED Peterson, AF Hernandez, GC Fonarow, LH Schwamm, EE Smith
Stroke 43 (9), 2293-2299
CITATIONS: 180
YEAR: 2012

Hyperdense sylvian fissure MCA “dot” sign: a CT marker of acute ischemia
PA Barber, AM Demchuk, ME Hudon, JHW Pexman, MD Hill, AM Buchan
Stroke 32 (1), 84-88
CITATIONS: 177
YEAR: 2001

ASPECTS on CTA source images versus unenhanced CT:  added value in predicting final infarct extent and clinical outcome
SB Coutts, MH Lev, M Eliasziq, L Roccatagliata, MD Hill, LH Schwamm, JHW Pexman, WJ Koroshetz, ME Hudon, AM Buchan, R Gilberto Gonzalez, AM Demchuk
Stroke 35 (11), 2472-2476
CITATIONS: 174
YEAR: 004

Asymptomatic hemorrhage after thrombolysis may not be benign: prognosis by hemorrhage type in the Canadian alteplase for stroke effectiveness study registry
I Dzialowski, JHW Pexman, PA Barber, AM Demchuk, AM Buchan, MD Hill, CASES Investigators
Stroke 38 (1), 75-79
CITATIONS: 171
YEAR: 2007

Leukoaraiosis and intracerebral hemorrhage after thrombolysis in acute stroke
V Palumbo, JM Boulanger, MD Hill, D Inzitari, AM Buchan
Neurology 68 (13), 1020-1024
CITATIONS: 160
YEAR: 2007

Recurrent cerebral ischemia in medically treated patent foramen ovale:  a meta-analysis
MA Almekhlafi, SB Wilton, DM Rabi, WA Ghali, DL Lorenzetti, MD Hill
Neurology 73 (2), 89-97
CITATIONS: 149
YEAR: 2009

The Alberta Stroke Program Early CT Score in clinical practice:  what have we learned?
V. Puetz, I Dzialowski, MD Hill, AM Demchuk
International Journal of Stroke 4 (5), 354-364
CITATIONS: 146
YEAR: 2009

When to expect negative diffusion-weighted images in stroke and transient ischemic attack
PN Sylaja, SB Coutts, A Krol, MD Hill, AM Demchuk
Stroke 39 (6), 1898-1900
CITATIONS: 137
YEAR: 2008

 

 

 

 

Highly Cited Papers from our Faculty Members

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Randomized assessment of rapid endovascular treatment of ischemic stroke
M Goyal, AM Demchuk, BK Menon, M Eesa, JL Rempel, J Thornton, ...
New England Journal of Medicine 372 (11), 1019-1030
CITATIONS: 5579
YEAR: 2015

Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke
JL Saver, M Goyal, A Bonafe, HC Diener, EI Levy, VM Pereira, GW Albers, ...
New England Journal of Medicine 372 (24), 2285-2295
CITATIONS: 4628
YEAR: 2015

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
M Goyal, BK Menon, WH van Zwam, DWJ Dippel, PJ Mitchell, ...
The Lancet 387 (10029), 1723-1731
CITATIONS: 4495
YEAR: 2016

Thrombectomy within 8 hours after symptom onset in ischemic stroke
TG Jovin, A Chamorro, E Cobo, MA de Miquel, CA Molina, A Rovira, ...
New England Journal of Medicine 372 (24), 2296-2306
CITATIONS: 4442
YEAR: 2015

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
JM Wardlaw, EE Smith, GJ Biessels, C Cordonnier, F Fazekas, R Frayne, ...
The Lancet Neurology 12 (8), 822-838
CITATIONS: 3462
YEAR: 2013

2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice …
RH Eckel, JM Jakicic, JD Ard, JM de Jesus, NH Miller, VS Hubbard, ...
Journal of the American College of Cardiology 63 (25 Part B), 2960-2984
CITATIONS: 3236
YEAR: 2014

Stenting versus endarterectomy for treatment of carotid-artery stenosis
TG Brott, RW Hobson, G Howard, GS Roubin, WM Clark, W Brooks, ...
New England Journal of Medicine 363 (1), 11-23
CITATIONS: 3230
YEAR: 2010

Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging
GW Albers, MP Marks, S Kemp, S Christensen, JP Tsai, ...
New England Journal of Medicine 378 (8), 708-718
CITATIONS: 3199
YEAR: 2018

Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy
PA Barber, AM Demchuk, J Zhang, AM Buchan, ASPECTS Study Group
The Lancet 355 (9216), 1670-1674
CITATIONS: 2349
YEAR: 2000

Endovascular therapy after intravenous t-PA versus t-PA alone for stroke
JP Broderick, YY Palesch, AM Demchuk, SD Yeatts, P Khatri, MD Hill, ...
New England Journal of Medicine 368 (10), 893-903
CITATIONS: 1571
YEAR: 2013