Meet the Team

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Dr. Mark Yarema

Dr. Mark Yarema is the Section Chief for Clinical Pharmacology and Toxicology and the Medical Director of the Poison and Drug Information Service (PADIS). He is a Clinical Professor in the Department of Emergency Medicine and a member of the O’Brien Institute of Public Health at the University of Calgary. His research interests include acetaminophen poisoning, pharmacogenomics, drugs of abuse, and toxic alcohols.

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Dr. Scott Lucyk

Dr. Scott Lucyk is the Associate Medical Director at PADIS. He is a Clinical Associate Professor in the Department of Emergency Medicine. He completed his Medical Toxicology fellowship at the New York City Poison Control Centre and his interests include medical education and resident teaching

Spyker DA, Dart RC, Yip L, Reynolds K, Brittain S, Yarema MC. Population pharmacokinetic analysis of acetaminophen overdose with immediate release, extended release and modified release formulations, Clinical Toxicology 2022, DOI:10.1080/15563650.2022.2114361

Sivilotti M, Yarema M, Juurlink D. Five things to know about acetaminophen overdose. CMAJ 2022 April 19;194:E554. doi: 10.1503/cmaj.210703.

Syafira N, Graudins A, Yarema M, Wong A. Comparing development of liver injury using the two versus three bag acetylcysteine regimen despite early treatment in paracetamol overdose, Clinical Toxicology 2021. DOI:10.1080/15563650.2021.1998518

Yarema MC, Johnson DW, Sivilotti MLA, Nettel-Aguirre A, DeWitt C, Gosselin S, Murphy N, Victorino C, Bailey B, Dong K, Haney E, Purssell R, Thompson M, Lord JA, Spyker DA, Rumack BH. Predicting Mortality from Acetaminophen Poisoning Shortly After Hospital Admission. Br J Clin Pharmacol. 2021;1–12.

Fan M, Yarema MC, Box A, Hume S, Aitchison KJ, Bousman CA. Identification of high-impact gene–drug pairs for pharmacogenetic testing in Alberta, Canada. Pharmacogenetics and Genomics 2020.

Liu YS, Lin KY, Masur J, Barby S, Chuang R, Johnson D, Lucyk S, Sivilotti M, Yarema MC. Outcomes after Recurrent Methanol Exposures not treated with Alcohol Dehydrogenase Inhibitors or Hemodialysis. J Emerg Med 2020. https://doi.org/10.1016/j.jemermed.2020.03.024.

Mutsaers A, Green J, Sivilotti M, Yarema M, Tucker D, Johnson D, Spyker D, Rumack B. Changing nomogram risk zone with serial testing following acute acetaminophen overdose. Clin Toxicol 2019. DOI: 10.1080/15563650.2018.1529320

Yarema MC, Chopra P, Sivilotti MLA, Johnson DW, Nettel-Aguirre A, Victorino C, Bailey B, Gosselin S, Purssell R, Thompson M, Spyker DA, Rumack BH. Anaphylactoid reactions to intravenous N-acetylcysteine during treatment of acute acetaminophen poisoning. J Med Toxicol 2018.14;120-127. DOI 10.1007/s13181-018-0653-9

Yarema MC, Green JP, Sivilotti MLA, Johnson DW, Nettel-Aguirre A, Victorino C, Spyker DA, Rumack BH. Can a serum acetaminophen concentration obtained less than 4 hours post-ingestion determine which patients do not require treatment with acetylcysteine? Clin Toxicol 2017; 55(2):102-108.

Liu YS, Lin KY, Masur J, Barby S, Chuang R, Johnson D, Lucyk S, Sivilotti M, Yarema MC. Outcomes after Recurrent Methanol Exposures not treated with Alcohol Dehydrogenase Inhibitors or Hemodialysis. J Emerg Med 2020;58(6):910-16. https://doi.org/10.1016/j.jemermed.2020.03.024.

Lucyk S. Decontamination Principles: Prevention of Dermal, Ophthalmic, and Inhalational Absorption. In: Nelson LS, Howland MA, Lewin N, Smith S, Goldfrank L, Hoffman R, editors. Goldfrank’s Toxicologic Emergencies, 11e. New York: McGraw-Hill Education; 2019.

Morrison LK, Kromm J, Gaudet J, Zuege D, Button B, Warshawski F and Lucyk SN. Rescue Extracorporeal Membrane Oxygenation Therapy in Methamphetamine Toxicity. CJEM 2018;20(S2):S14-19. doi: 10.1017/cem.2017.356.

Dewaal C, McGillis E, Mink M, Lucyk S. Octreotide for the treatment of intentional insulin aspart overdose in a non-diabetic patient. CJEM. 2018;20(4):643-7.

Lucyk S. Calculated decisions: Acetaminophen Overdose and N-Acetylcysteine (NAC) Dosing. Emerg Med Pract. 2018;20(4 Suppl): S3-S5.

Lucyk S. Concentrated Hydrogen Peroxide Ingestion. In: Dye L, Murphy C, Calello D, Levine M, Skolnik A, editors. Case Studies in Medical Toxicology. Switzerland: Springer International Publishing; 2017.

Lucyk SN, Nelson LS. Toxicosurveillance in the US Opioid Epidemic. Int J Drug Policy. 2017;46:168-71.

Morrison LK, Kromm J, Gaudet J, Zuege D, Button B, Warshawski F and Lucyk SN. Rescue Extracorporeal Membrane Oxygenation Therapy in Methamphetamine Toxicity. CJEM. 2017. Accepted for publication.

Lucyk SN, Nelson LS. Novel Synthetic Opioids: An Opioid Epidemic Within an Opioid Epidemic. Ann Emerg Med. 2017;69(1):91-93.

Lucyk S, Nelson L. Consequences of unsafe prescribing of transdermal fentanyl. CMAJ. 2016;188(9):638-9.

Lucyk SN, Yarema MC, Sivilotti ML, Johnson DW, Nettel-Aguirre A, Victorino C, Bailey B, Dart RC, Heard K, Spyker DA, Rumack BH. Outcomes of Patients With Premature Discontinuation of the 21-h Intravenous N-Acetylcysteine Protocol After Acute Acetaminophen Overdose. J Emerg Med. 2016;50(4):629-37

Lucyk S, Nelson LS. Opioids. In: Brent J, Burkhart K, Dargan P, Hatten B, Megarbane B, Palmer R, editors. Critical Care Toxicology, 2e. Switzerland: Springer International Publishing; 2015.

Lucyk S, Nelson LS. Opioid Receptor Antagonists. In: Brent J, Burkhart K, Dargan P, Hatten B, Megarbane B, Palmer R, editors. Critical Care Toxicology, 2e. Switzerland: Springer International Publishing; 2015.

Dr. Morgan Riggan

Dr. Morgan Riggan

Dr. Morgan Riggan is an emergency physician at London Health Sciences Centre in London, Ontario. She is an Assistant Professor in the Department of Medicine, Division of Emergency Medicine at Western University. Morgan completed her Medical Toxicology fellowship at New York University while working at the New York City Poison Control Centre. Her toxicology interests include bupropion toxicity and gastric decontamination strategies.

 

Dr. Eric McGillis

Dr. Eric McGillis

Dr. Eric McGillis is the Program Director of the Clinical Pharmacology and Toxicology subspecialty and is an emergency physician at Alberta Health Services in the Calgary Zone. He is a Clinical Assistant Professor in the Department of Emergency Medicine at the Cumming School of Medicine. Eric completed his Medical Toxicology Fellowship at Health Partners Institute in St. Paul Minnesota and at the Minnesota Poison Information System, Minneapolis MN. His interests are mitochondrial toxins, bupropion, and drug safety.

Riggan MA, Perreault G, Wen A, Raco V, Vassallo S, Gerona R, Hoffman RS. Case Report: Analytically Confirmed Severe Albenzadole Overdose Presenting with Alopecia and Pancytopenia. Am J Trop Med Hyg, 2019 Nov 4, Principal Author, DOI: 10.4269/ajtmh.19-0198.

Morgan A.A. Riggan, David Gummins. Chapter 105 - Hydrocarbons. In: Lewis S. Nelson, Mary Ann Howland, Neal A. Lewin, Silas W. Smith, Lewis R. Goldfranks, Robert S. Hoffman, editor(s). Goldfrank’s Toxicologic Emergencies. 11. (United States): McGraw Hill; 2019, Co-Principal Author, DOI: ISBN 978-1-259-85961-8.

Fox LM, Riggan MA, Nelson LS, Biary R. Articles You May Have Missed. J Med Toxicol, 2016 Sep 1; 12 (3): 318-23, Coauthor, DOI: 10.1007/s13181-016-0570-8.

Saleh D, Lucyk S, McGillis E. Methemoglobinemia caused by sodium nitrite overdose. CMAJ. 2022 Aug 8;194(30):E1066-E1067. doi: 10.1503/cmaj.220434. PMID: 35940618; PMCID: PMC9365438.

McCabe DJ, McGillis E, Willenbring BA. The Timing of Clinical Effects of Bupropion Misuse Via Insufflation Reported to a Regional Poison Center. J Emerg Med. 2022 Feb;62(2):175-181. doi: 10.1016/j.jemermed.2021.07.052. Epub 2021 Sep 15. PMID: 34538516.

McCabe DJ, McGillis E, Willenbring BA. Clinical Effects of Intravenous Bupropion Misuse Reported to a Regional Poison Center. Am J Emerg Med. 2021 Mar 24;47:86-89. doi: 10.1016/j.ajem.2021.03.061. Online ahead of print. PMID: 33794474

Wong JVS, Olives TD, McGillis ES. A Gorilla Glue Bezoar Results in Gastric Outlet Obstruction and Gastrostomy. Clin Toxicol (Phila). 2021 Feb 19:1-3. doi:10.1080/15563650.2021.1888969. Online ahead of print. PMID: 33605817 No abstract available.

McGillis E, Sztanjnkrycer M. Beta-blockers. In: Wolfson B et al., editors. Harwood-Nuss’ Clinical Practice of Emergency Medicine, 7e. Philadelphia: Wolters Kluwer; 2020. Publication Accepted.

Olives T, Willhite LA, Lee SC, Evans DK, Jensen A, Regelman HT, McGillis ES. Point-of-Sale Naloxone: Novel Community-based Research to Identify Naloxone Availability. West J Emerg Med. 2020 Aug 24;21(5):1188-1194. doi: 10.5811/westjem.7.2020.47252. PMID: 32970574 Free PCM article.

McGillis ES, Olives TD, Love SA, Cole JB. A Young Man with Accelerated Hyperthermia, Hypercapnia, and Profound Muscle Rigidity after Ingestion of a Weight Loss Agent. Ann Am Thorac Soc. 2020 Mar;17(3):361-366

McGillis E, Baumann T, LeRoy J. Death Associated with Nadolol for Infantile Hemangioma: A Case for Improving Safety. Pediatrics. 2020 Jan;145(1)

McGillis ES, Olives TD, Cole JB. Reply: Matching Minute Ventilation in the Hyper-metabolic State of Dinitrophenol Poisoning. Ann AmThorac Soc. 2020 Sep 2. doi: 10.1513/AnnalsATS.202008-1004LE. Online ahead of print. PMID: 32877206 No abstract available.

Dewaal CM, McGillis E, Mink M, Lucyk S. Octreotide for the treatment of intentional insulin aspart overdose in a non-diabetic patient. CJEM. 2018 Jul;20(4):643-647

Dr. Riley Hartmann

Dr. Riley Hartmann

Dr. Riley Hartmann is an emergency physician in Saskatoon, Saskatchewan. Additionally, he is the provincial lead for toxicology for Saskatchewan. Riley completed his Clinical Pharmacology and Toxicology Fellowship at the University of Calgary and continues to provide consultation services for both PADIS and the Clinical Pharmacology Consult service at the University of Calgary. His research interests include quality improvement and patient safety, and medical education.

Emergency Department Pediatric Visits in Alberta for Cannabis After Legalization. Yeung MEM, Weaver CG, Hartmann R, Saah-Haines R, Lang E. Pediatrics. 2021 Sep 20:e2020045922. Epub ahead of print. PMID 34544846

A transparent and defensible process for applicant selection within a Canadian emergency medicine residency program. QS Paterson, R Hartmann, R Woods, LJ Martin, B Thoma, Canadian Journal of Emergency Medicine 22 (2), 215-223

Impact of an emergency department opioid prescribing guideline on emergency physician behaviour and incidence of overdose in the Saskatoon Health Region: a retrospective pre …RJ Hartmann, JD Elder, LA Terrett, CMAJ open 9 (1), E79