CPT Pearls of the Week
The Clinical Pharmacology and Toxicology (CPT) Pearls of the Week are short educational summaries of specific CPT topics. They are developed by physician members of the AHS Section of Clinical Pharmacology and Toxicology and are not meant to be detailed management guidelines or comprehensive reviews. The Pearls are located within the various categories on this page. These categories represent the breadth and depth of the specialty of CPT as well as the major core competencies of CPT training in Canada.
Acute Generalized Exanthematous Pustolosis (AGEP)
Causality Assessment Tools Part I: Naranjo Scale
Causality Assessment Tools Part II: Liverpool Tool
Causality Assessment Tools Part III: WHO-UMC Assessment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Drug Induced Alteration in Taste and Smell
Drug Induced Extrapyramidal Symptoms (EPS)
Drug Induced Movement Disorders
Drug Induced Renal Tubular Acidosis
Drug Induced Urinary Retention
Extravasation Injuries: Part I
Extravasation Injuries: Part II
Medication Errors & Solutions: Part I
Medication Errors & Solutions: Part II
Medication Induced Hairy Tongue
Medication Safety Part 1: Appropriate Medication Prescribing
Medication Safety Part II: Deprescribing
Metformin Induced Hyperlactatemia
Propofol Related Infusion Syndrome
Restarting a Medication After an Adverse Event
Restarting a Medication After an Overdose
SGLT2 Inhibitors & Euglycemic DKA
Statin Associated Muscle Symptoms
Acetaminophen-Related Pyroglutamic Acidosis (PGA)
Carbon Monoxide Part I: Sources & Symptoms
Carbon Monoxide Part II: Testing & Treatment
ECG Findings in Sodium Channel Blockade Overdose
Extracorporeal Removal of Drugs
Fomepizole for Acetaminophen Toxicity
IV Acetylcysteine Neurotoxicity
IV Acetylcysteine & Anaphylactoid Reactions
Newer IV Acetylcysteine Regimens: Part I
Newer IV Acetylcysteine Regimens: Part II
Physostigmine for Anticholinergic Delirium
Toxicologic Hyperthermic Syndromes: Part I
Toxicologic Hyperthermic Syndromes: Part II
Amiodarone Part I: Facts and Pharmacology
Amiodarone Part II: Neurotoxicity
Amiodarone Part III: Ophthalmologic Toxicity
Amiodarone Part IV: Thyroid Toxicity
Amiodarone Part V: Lung Toxicity
Antihypertensives Part I: CCBs
Antihypertensives Part II: Cardioselective Beta Blockers
Antihypertensives Part III: Thiazides and Thiazide Like Diuretics
Antihypertensives Part IV: MRAs
Antihypertensives Part V: Alpha 2 Receptor Agonists
Antihypertensives Part VI: Loop Diuretics
Bispecific T cell Engagers (BiTEs)
Immune Checkpoint Inhibitors Part I: Pharmacology and Indications
Immune Checkpoint Inhibitors Part II: Toxicity
Immune Checkpoint Inhibitors Part III: Management of Toxicity
Pros and Cons of DOACs vs Warfarin vs LMWH
Tetracyclines in Pediatric Patients