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Otolaryngology - Head & Neck Surgery | Research

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Research

The Ohlson Research Initiative is a clinical research program focused on head and neck cancer.  The initiative functions within the University of Calgary, Cumming School of Medicine as well as the The Arnie Charbonneau Cancer.

Learn more about the Ohlson Research Initiative here.  Learn more about Cumming School of Medicine research here.


Current Resident Research

  1. Research Interest

    Education, medical technology, virtual reality, artificial intelligence, health economics, and medical education.

  2. Publications

    • Tabanfar R, Chan H, Lin V, Le T, Irish J. Development and Face Validation of a Virtual Reality Epley Maneuver System (VREMS) for Home Epley Treatment of Benign Paroxysmal Positional Vertigo: A Randomized Controlled Trial. American Journal of Otolaryngology. 2017 Nov. 
    • Tabanfar R, Qiu J, Chan H, Aflatouni N, Weersink R, Hasan W, Irish JC. Real-time continuous image guided surgery (RTC-IGS): preclinical investigation in glossectomy. The Laryngoscope. 2017 Oct;127(10): E347-E353. 
    • Mednick Z, Tabanfar R, Alexander A, Simpson S, Baxter S. The Creation and Validation of a Simulator for Corneal Rust Ring Removal. Canadian Journal of Ophthalmology. 2017 Oct;52(5):447-452. 
    • Hudson C, Gauvin S, Tabanfar R, Lee J, Poffenroth A, O’Riordan, A. Promotion of role clarification in the healthcare team challenge. Journal of Interprofessional Care. 2017 May;31(3):401-403.
  1. Research Interest

    Laryngology. Development of an AI diagnostic tool for voice disorders.

  2. Publications

    • Compton, E, Cruz, T, Andreassen M, Beveridge S, Bosch D, Randall D, Livingstone D. Developing an artificial intelligence tool to predict vocal cord pathology in primary care settings. The Laryngoscope. September 2022.
    • Compton E, Beveridge S, Andreassen M, Gelfand G, McFadden S, Bosch D, Randall D. Long term voice outcomes following cricotracheal resection for subglottic stenosis: A retrospective analysis. The Laryngoscope. August 2021. 
    • Compton E, Agrawal S, Ladak H, Chan S, Hoy M, Nakoneshny S, Siegel L, Dort J, Lui J. Assessment of a virtual reality temporal bone surgical simulator:  a national face and content validity study. Journal of Otolaryngology-Head and Neck Surgery. March 2020. 
    • Lui J, Compton E, Ryu W, Hoy M. Current Adjunctive Training Landscape in Canadian Otolaryngology–Head & Neck Residency Programs: A National Survey of Program Directors and Residents. J Otolaryngol Head Neck Surg. 2018 Oct 1;47(1):61. 
       
  1. Research Interest

    Head and Neck, laryngology, QI, education, and pediatrics.

  2. Publications

    • Ramazani F, Yunker W, Liu C. Evaluating the Sensitivity and Specificity of US as a Diagnostic Tool for Pediatric Neck Abscesses. JAMA- Otolaryngology- Head and Neck Surgery, 2022. 
    • Ramazani, F., Hamour, A., Jeffery, C.C. et al. Development of a patient reported outcome instrument for chronic sialadenitis. J of Otolaryngol - Head & Neck Surg 51, 4 (2022). https://doi.org/10.1186/s40463-022-00555-z
    • Ramazani F, Isaac A, Johannsen W, El-Hakim H. Side effects and complications of injection laryngoplasty for treatment of congenital type 1 laryngeal clefts. Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109886. doi: 10.1016/j.ijporl.2020.109886. Epub 2020 Jan 16. PMID: 31968273.
    • Jarman M, Mathe, N, Ramazani F, Pakseresht M, Robson P. J., Johnson S. T, & Bell R. C. (2018). Dietary Patterns Prior to Pregnancy and Associations with Pregnancy Complications. Nutrients, 10(7). 
    • Azhdarzadeh M, Saei AA, Sharifi S, Hajipour MJ, Alkilany AM, Sharifzadeh M, Ramazani F, Laurent S, Mashaghi A, Mahmoudi M. (2015) Nanotoxicology: Advances and Pitfalls in Research Methodology. Nanomedicine. 10(18), 2931-2952.
  1. Research Interest

    Otology. Management of Sudden Sensorineural Hearing Loss. Objective measurements of eustachian tube function.

  2. Publications

    • de Champlain, K, Sunba, S, Beveridge, S, Andreassen, M, Bosch, D, Randall, DR. Effect of socioeconomic status on wait times for patients undergoing treatment for laryngeal conditions in a universal healthcare system. Laryngoscope Investigative Otolaryngology. 2022; 1- 6. doi:10.1002/lio2.930 
    • Lui J, de Champlain K, Chau JK. (2018). Management of Adult Sensorineural Hearing Loss. In Evidence-Based Clinical Practice of Otolaryngology. (pp. 15 – 24). Elsevier, St. Louis, Missouri.
    • de Champlain K, Kurek KC, Yunker WK. Novel presentation of cranial fasciitis of the mandible: Case report and literature review. International Journal of Pediatric Otorhinolaryngology. 2018; 115:33-37
  1. Research Interest

    Head and Neck. Clinical outcomes in Head and Neck Surgery, Functional outcomes of Head and Neck Surgery reconstruction, role of precision medicine in Head and Neck Cancer treatment .

  2. Publications

    • Mahboubi K, Ahrens B, Lane C, MacLellan D, Anderson P, Romao RL. A follow-up geospatial analysis of hypospadias and cryptorchidism prevalence rates in a Canadian province with stable population. Journal of Pediatric Urology 2021
    • Mahboubi K, Langley R. A collision tumour: Seborrheic keratosis and malignant melanoma in situ. The Lancet 2019
    • Oluwole OA, Mahboubi K, Favetta LA, Revay T, Kroetsch T, King WA. Highly dynamic temporal changes of TSPY copy number in aging bulls. PLoS ONE 2017
    • Oluwole OA, Revay T, Mahboubi K., Favetta LA, King WA. Somatic Mosaicism in bulls estimated from genome-wide CNV array and TSPY gene copy numbers. Cytogenet Genome Res 2016
    • Ferris J, Mahboubi K, MacLusky N, King WA, Favetta LA. BPA exposure during in vitro oocyte maturation results in dose-dependent alterations to embryo development rates, apoptosis rate, sex ratio and gene expression. Reproductive Toxicology 2016
    • Stojsin A1, Mahboubi K1, Costa NN, Gillis DJ, Carter TF, Neal MS, Miranda MS, Ohashi OM, Favetta LA. Systemic and local anti-Mullerian hormone reflects differences in the reproduction potential of Zebu and European type cattle. Anim Reprod Sci 2016
  1. Research Interest

    Rhinology, QI, education, and sleep surgery. Patient-reported outcome measures in patients with chronic rhinosinusitis (CRS). Medical therapies for CRS. Surgical management of CRS

  2. Publicatons

    • Bell C, Prokopchuk-Gauk O, Cload B, Stirling A, Davis PJ. Optimum accuracy of massive transfusion protocol activation: the clinician’s view. Cureus. 2018 Dec 5;10(12).
  1. Research Interest

    QI and education.

  2. Publications

    • Randall DR, Chan R, Gomes D, Walker K. Natural History of Cricopharyngeus Muscle Dysfunction Symptomatology. Dysphagia. 2022 Aug;37(4):937-945. doi: 10.1007/s00455-021-10355-8. Epub 2021 Sep 8. PMID: 34495387.
    • Chan RK, Ahrens B, MacEachern P, Bosch JD, Randall DR. Prevalence and incidence of idiopathic subglottic stenosis in southern and central Alberta: a retrospective cohort study. J Otolaryngol Head Neck Surg. 2021 Nov 12;50(1):64. doi: 10.1186/s40463-021-00544-8. PMID: 34772459; PMCID: PMC8588657.
    • Chan RK, Sterniczuk R, Enkhbold Y, Jeffers RT, Basu P, Duong B, Chow SL, Smith VM, Antle MC. Phase shifts to light are altered by antagonists to neuropeptide receptors. Neuroscience. 2016 Jul 7;327:115-24. doi: 10.1016/j.neuroscience.2016.04.010. Epub 2016 Apr 16. PMID: 27090819.
  1. Research Interest

    Otology and epigenetics. Use of DNA methylation as a clinical tool. Novelties in management of eustachian tube dysfunction, such as ET balloon dilation, in order to better address this disease underlying many otological sequelae.

  2. Publications

    • Pattar S, Aleinati M, Iqbal F, et al. Identification of cell-free DNA methylation patterns unique to the human left ventricle as a potential indicator of acute cellular rejection. Clin Transplant. 2021;35(6):e14295. doi:10.1111/ctr.14295
    • Maredia A, Guzzardi D, Aleinati M, et al. Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy. Clin Epigenetics. 2021;13(1):147. Published 2021 Jul 28. doi:10.1186/s13148-021-01137-y
  1. Research Interest

    Head and Neck and QI.

  1. Research Interest

    Otology, facial plastics, and education.