Otolaryngology - Head & Neck Surgery | Research

Research Interest

Otology and epigenetics. Use of DNA methylation as a clinical tool. Novelties in management of eustachian tube dysfunction, such as ET balloon dilation, in order to better address this disease underlying many otological sequelae.

Publications

• Pattar S, Aleinati M, Iqbal F, et al. Identification of cell-free DNA methylation patterns unique to the human left ventricle as a potential indicator of acute cellular rejection. Clin Transplant. 2021;35(6):e14295. doi:10.1111/ctr.14295
• Maredia A, Guzzardi D, Aleinati M, et al. Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy. Clin Epigenetics. 2021;13(1):147. Published 2021 Jul 28. doi:10.1186/s13148-021-01137-y

Research Interest

QI and education.

Publications

• Randall DR, Chan R, Gomes D, Walker K. Natural History of Cricopharyngeus Muscle Dysfunction Symptomatology. Dysphagia. 2022 Aug;37(4):937-945. doi: 10.1007/s00455-021-10355-8. Epub 2021 Sep 8. PMID: 34495387.
• Chan RK, Ahrens B, MacEachern P, Bosch JD, Randall DR. Prevalence and incidence of idiopathic subglottic stenosis in southern and central Alberta: a retrospective cohort study. J Otolaryngol Head Neck Surg. 2021 Nov 12;50(1):64. doi: 10.1186/s40463-021-00544-8. PMID: 34772459; PMCID: PMC8588657.
• Chan RK, Sterniczuk R, Enkhbold Y, Jeffers RT, Basu P, Duong B, Chow SL, Smith VM, Antle MC. Phase shifts to light are altered by antagonists to neuropeptide receptors. Neuroscience. 2016 Jul 7;327:115-24. doi: 10.1016/j.neuroscience.2016.04.010. Epub 2016 Apr 16. PMID: 27090819.

Research Interest

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