Otolaryngology - Head & Neck Surgery | Research

Research Interest

Head and Neck, laryngology, QI, education, and pediatrics.

Publications

• Ramazani F, Yunker W, Liu C. Evaluating the Sensitivity and Specificity of US as a Diagnostic Tool for Pediatric Neck Abscesses. JAMA- Otolaryngology- Head and Neck Surgery, 2022. 
• Ramazani, F., Hamour, A., Jeffery, C.C. et al. Development of a patient reported outcome instrument for chronic sialadenitis. J of Otolaryngol - Head & Neck Surg 51, 4 (2022). https://doi.org/10.1186/s40463-022-00555-z
• Ramazani F, Isaac A, Johannsen W, El-Hakim H. Side effects and complications of injection laryngoplasty for treatment of congenital type 1 laryngeal clefts. Int J Pediatr Otorhinolaryngol. 2020 Apr;131:109886. doi: 10.1016/j.ijporl.2020.109886. Epub 2020 Jan 16. PMID: 31968273.
• Jarman M, Mathe, N, Ramazani F, Pakseresht M, Robson P. J., Johnson S. T, & Bell R. C. (2018). Dietary Patterns Prior to Pregnancy and Associations with Pregnancy Complications. Nutrients, 10(7).
• Azhdarzadeh M, Saei AA, Sharifi S, Hajipour MJ, Alkilany AM, Sharifzadeh M, Ramazani F, Laurent S, Mashaghi A, Mahmoudi M. (2015) Nanotoxicology: Advances and Pitfalls in Research Methodology. Nanomedicine. 10(18), 2931-2952.

Research Interest

Otology. Management of Sudden Sensorineural Hearing Loss. Objective measurements of eustachian tube function.

Publications

• de Champlain, K, Sunba, S, Beveridge, S, Andreassen, M, Bosch, D, Randall, DR. Effect of socioeconomic status on wait times for patients undergoing treatment for laryngeal conditions in a universal healthcare system. Laryngoscope Investigative Otolaryngology. 2022; 1- 6. doi:10.1002/lio2.930 
• Lui J, de Champlain K, Chau JK. (2018). Management of Adult Sensorineural Hearing Loss. In Evidence-Based Clinical Practice of Otolaryngology. (pp. 15 – 24). Elsevier, St. Louis, Missouri.
• de Champlain K, Kurek KC, Yunker WK. Novel presentation of cranial fasciitis of the mandible: Case report and literature review. International Journal of Pediatric Otorhinolaryngology. 2018; 115:33-37

Research Interest

Head and Neck. Clinical outcomes in Head and Neck Surgery, Functional outcomes of Head and Neck Surgery reconstruction, role of precision medicine in Head and Neck Cancer treatment .

Publications

• Mahboubi K, Ahrens B, Lane C, MacLellan D, Anderson P, Romao RL. A follow-up geospatial analysis of hypospadias and cryptorchidism prevalence rates in a Canadian province with stable population. Journal of Pediatric Urology 2021
• Mahboubi K, Langley R. A collision tumour: Seborrheic keratosis and malignant melanoma in situ. The Lancet 2019
• Oluwole OA, Mahboubi K, Favetta LA, Revay T, Kroetsch T, King WA. Highly dynamic temporal changes of TSPY copy number in aging bulls. PLoS ONE 2017
• Oluwole OA, Revay T, Mahboubi K., Favetta LA, King WA. Somatic Mosaicism in bulls estimated from genome-wide CNV array and TSPY gene copy numbers. Cytogenet Genome Res 2016
• Ferris J, Mahboubi K, MacLusky N, King WA, Favetta LA. BPA exposure during in vitro oocyte maturation results in dose-dependent alterations to embryo development rates, apoptosis rate, sex ratio and gene expression. Reproductive Toxicology 2016
• Stojsin A1, Mahboubi K1, Costa NN, Gillis DJ, Carter TF, Neal MS, Miranda MS, Ohashi OM, Favetta LA. Systemic and local anti-Mullerian hormone reflects differences in the reproduction potential of Zebu and European type cattle. Anim Reprod Sci 2016

Research Interest

Perioperative medical and surgical management of chronic rhinosinusitis, patient-reported outcome measures in patients with chronic rhinosinusitis, surgeon and patient education of paranasal sinus anatomy, perioperative management and optimization of patients undergoing sleep apnea surgery.

Publicatons

• Bell CM, Yip J. Timing of surgery and outcomes in chronic rhinosinusitis: a narrative review and meta-analysis. Journal of Otolarynology-Head and Neck Surgery. 2024, forthcoming.
• Bell CM, Thamboo AV, Monteiro E, Yip J. Prescribing Practices and Barriers of Biologics for Chronic Rhinosinusitis Amongst Otolaryngologists. The Laryngoscope. 2024 Feb 27.
• Shin D, Batista AV, Bell CM, Koonar ER, Chen JM, Chan S, Dort JC, Lui JT. Examining the utility of a photorealistic virtual ear in otologic education. Journal of Otolaryngology-Head & Neck Surgery. 2023 Feb 22;52(1):18.
• Bell C and Chau J. Variation in patient presentation and the use of computer tomography in the urgent care diagnosis and treatment of peritonsillar abscess. Authorea. April 18, 2023. DOI: 10.22541/au.167527264.46625849/v2
• Bell C, Prokopchuk-Gauk O, Cload B, Stirling A, Davis PJ. Optimum accuracy of massive transfusion protocol activation: the clinician’s view. Cureus. 2018 Dec 5;10(12).

Research Interest

QI and education.

Publications

• Randall DR, Chan R, Gomes D, Walker K. Natural History of Cricopharyngeus Muscle Dysfunction Symptomatology. Dysphagia. 2022 Aug;37(4):937-945. doi: 10.1007/s00455-021-10355-8. Epub 2021 Sep 8. PMID: 34495387.
• Chan RK, Ahrens B, MacEachern P, Bosch JD, Randall DR. Prevalence and incidence of idiopathic subglottic stenosis in southern and central Alberta: a retrospective cohort study. J Otolaryngol Head Neck Surg. 2021 Nov 12;50(1):64. doi: 10.1186/s40463-021-00544-8. PMID: 34772459; PMCID: PMC8588657.
• Chan RK, Sterniczuk R, Enkhbold Y, Jeffers RT, Basu P, Duong B, Chow SL, Smith VM, Antle MC. Phase shifts to light are altered by antagonists to neuropeptide receptors. Neuroscience. 2016 Jul 7;327:115-24. doi: 10.1016/j.neuroscience.2016.04.010. Epub 2016 Apr 16. PMID: 27090819.

Research Interest

Otology and epigenetics. Use of DNA methylation as a clinical tool. Novelties in management of eustachian tube dysfunction, such as ET balloon dilation, in order to better address this disease underlying many otological sequelae.

Publications

• Pattar S, Aleinati M, Iqbal F, et al. Identification of cell-free DNA methylation patterns unique to the human left ventricle as a potential indicator of acute cellular rejection. Clin Transplant. 2021;35(6):e14295. doi:10.1111/ctr.14295
• Maredia A, Guzzardi D, Aleinati M, et al. Aorta-specific DNA methylation patterns in cell-free DNA from patients with bicuspid aortic valve-associated aortopathy. Clin Epigenetics. 2021;13(1):147. Published 2021 Jul 28. doi:10.1186/s13148-021-01137-y